Active Recombinant Human WNK3 Protein, His tagged

Cat.No. : WNK3-01H
Product Overview : Recombinant Human, Catalytic Domain (amino acids 1-434), His-tagged, expressed in insect cells. Activated in vitro via autophosphorylation.
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Species : Human
Source : Insect cells
Tag : His
Protein Length : 1-434 aa
Description : This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants.
Form : 50 mM Tris (pH 7.5), 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT and 50% Glycerol.
Bio-activity : 30 nmoles of phosphate transferred to myelin basic protein (MBP) per minute per mg of total protein at 30 centigrade. Activity determined at a final protein concentration of 8.33 μg/mL.
Molecular Mass : 53.4 kDa
Purity : 80% as determined by a SDS-PAGE gel stained with SimplyBlue SafeStain.
Storage : At -80 centigrade
Concentration : 0.35 mg/mL total protein as measured using the Bradford protein assay with BSA as a standard. Calculated 6,550 nM.
Shipping : Dry ice
Gene Name WNK3 WNK lysine deficient protein kinase 3 [ Homo sapiens (human) ]
Official Symbol WNK3
Synonyms WNK3; WNK lysine deficient protein kinase 3; PRKWNK3, protein kinase, lysine deficient 3; serine/threonine-protein kinase WNK3; protein kinase with no lysine 3; PRKWNK3; FLJ30437; FLJ42662; KIAA1566
Gene ID 65267
mRNA Refseq NM_001002838
Protein Refseq NP_001002838
MIM 300358
UniProt ID Q9BYP7

Not For Human Consumption!

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