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ZNF12

Official Full Name

zinc finger protein 12
Overview

This gene is a member of the krueppel C2H2-type zinc-finger protein family and encodes a protein with eight C2H2-type zinc fingers and a KRAB domain. This nuclear protein is involved in developmental control of gene expression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms

ZNF12; zinc finger protein 12; zinc finger protein 325 , ZNF325; GIOT 3; KOX3; GIOT3; Gonadotropin inducible transcription repressor 3; Zinc finger protein 325; Zinc finger protein KOX3; ZNF325; zinc finger protein 11; gonadotropin-inducible ovary transcription repressor 3; HZF11; GIOT-3; Krox-7; Zfp-12; C530015C18;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ZNF12-3815H	Recombinant Human ZNF12, His-tagged	E.coli	His	93-156aa	$319 / 25μg
Mouse	ZFP12-18827M	Recombinant Mouse ZFP12 Protein	Mammalian Cell	His		Inquiry
Mouse	ZNF12-10397M	Recombinant Mouse ZNF12 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Mouse	ZNF12-10397M-B	Recombinant Mouse ZNF12 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

ZNF12 involved in several pathways and played different roles in them. We selected most pathways ZNF12 participated on our site, such as Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNF12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Gene Expression	MBD3;PLD6;SMARCA5;ZNF394;TBX5;ZNF614;GPR19;DNAJC8;ZNF597
Generic Transcription Pathway	ZNF426;NR2E3;ZNF311;ZNF620;ZNF613;ZNF740;NR2F1A;LAMTOR1;ZNF254

ZNF12 has several biochemical functions, for example, DNA binding, metal ion binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZNF12 itself. We selected most functions ZNF12 had, and list some proteins which have the same functions with ZNF12. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	HLFB;DMC1;POLR3K;OASL1;MCM2;ZNF224;NKX2.4B;PHOX2BA;TAL2
metal ion binding	VAV3;CD209;RPE65A;ADAR;HDAC7;DMRTA2;ESR2B;CSH1;TIMM8B
transcription factor activity, sequence-specific DNA binding	FOXS1;PA2G4A;PAX6;THRA;HMGB1;SMAD6A;FOXC2;MEF2D;POU3F3

ZNF12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNF12 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNF12.

Research Area

Ripoll, VM; Lambrianides, A; et al. Changes in regulation of human monocyte proteins in response to IgG from patients with antiphospholipid syndrome. BLOOD 124:3808-3816(2014).

Jackson, R; Braubach, OR; et al. Expression of sall4 in taste buds of zebrafish. DEVELOPMENTAL NEUROBIOLOGY 73:543-558(2013).