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ZNF259

Official Full Name

zinc finger protein 259
Overview

The zinc finger protein ZPR1 (ZNF259) binds to epidermal growth factor receptor (EGFR) and is localized to both cytoplasm and nucleus. The zinc fingers found in ZPR1 and the tyrosine kinase domain of EGFR mediate the interaction between ZPR1 and the recep
Synonyms

ZNF259; zinc finger protein 259; zinc finger protein ZPR1; ZPR1; MGC110983; RGD1562173;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ZNF259-6943H	Recombinant Human Zinc Finger Protein 259, GST-Tagged	E.coli	GST		Inquiry
Human	ZNF259-6946H	Recombinant Human Zinc Finger Protein 259, GST-Tagged	Wheat Germ	GST		Inquiry
Human	ZNF259-6945H	Recombinant Human Zinc Finger Protein 259, GST-Tagged	Wheat Germ	GST		Inquiry
Human	ZNF259-30759TH	Recombinant Human ZNF259, His-tagged	E.coli	His	29-459	Inquiry
Human	ZNF259-6944H	Recombinant Human Zinc Finger Protein 259, His-tagged	E.coli	His		Inquiry
Human	ZNF259-3830H	Recombinant Human ZNF259, His-tagged	E.coli	His	111-459aa	$319 / 25μg
Human	ZNF259-108HCL	Recombinant Human ZNF259 293 Cell Lysate	HEK293	Non		Inquiry
Mouse	ZFP259-18861M	Recombinant Mouse ZFP259 Protein	Mammalian Cell	His		Inquiry
Mouse	ZNF259-10405M	Recombinant Mouse ZNF259 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Mouse	ZNF259-10405M-B	Recombinant Mouse ZNF259 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

ZNF259 involved in several pathways and played different roles in them. We selected most pathways ZNF259 participated on our site, such as EGFR1 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNF259 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
EGFR1 Signaling Pathway	WNK1;SH3BGRL;KRT8;CRKL;TNK2;KRT17;EPPK1;PITPNAA;ERRFI1

ZNF259 has several biochemical functions, for example, protein binding, receptor tyrosine kinase binding, translation initiation factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZNF259 itself. We selected most functions ZNF259 had, and list some proteins which have the same functions with ZNF259. You can find most of the proteins on our site.

Function	Related Protein
protein binding	LOXL3;ARHGEF12;TMEM132D;GPSM2;FAM129A;SPAT-1;NCOA2;TUBB;ARFGAP1
receptor tyrosine kinase binding	TP53;FLT3LG;ANGPT1;PCNA;SHC3;LRP4;PTPN1;GAS6;ARHGEF16
translation initiation factor binding	DDX3X;LIN28A;EIF3C;TBL2;ZNF259;EIF2B3;EIF3B;POLR2D;TRIM32
zinc ion binding	RNF213;KMT2E;MT2A;ZNRF2B;RNF133;PHF19;RNFT1;GATA1;ZNF34

ZNF259 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNF259 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNF259.

MPP3; CDK5RAP2

Research Area

Islam, A; Schulz, S; et al. Interaction of VP8 with mRNAs of bovine herpesvirus-1. VIRUS RESEARCH 197:116-126(2015).

Abe, S; Tokoro, F; et al. Association of a polymorphism of the zinc finger protein 259 gene (ZNF259) with dislipidemia in Japanese individuals. EUROPEAN HEART JOURNAL 35:220-220(2014).