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ZNF346

Official Full Name

zinc finger protein 346
Overview

The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival.
Synonyms

ZNF346; zinc finger protein 346; JAZ; Zfp346; DKFZp547M223; Double stranded RNA binding zinc finger protein; Double stranded RNA binding zinc finger protein JAZ; Just another zinc finger protein; ZN346_HUMAN; OTTHUMP00000161434; OTTHUMP00000223533; OTTHUMP00000223535; OTTHUMP00000223537; double-stranded RNA-binding zinc finger protein JAZ;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

GST
His
Fc
Avi
SUMO
Myc
DDK
Non

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ZNF346-2306H	Recombinant Human ZNF346, His-tagged	E.coli	His	317aa	Inquiry
Human	ZNF346-3841H	Recombinant Human ZNF346, GST-tagged	E.coli	GST	1-294aa	$319 / 25μg
Human	ZNF346-2016HCL	Recombinant Human ZNF346 cell lysate		Non		Inquiry
Mouse	ZFP346-18897M	Recombinant Mouse ZFP346 Protein	Mammalian Cell	His		Inquiry
Mouse	Zfp346-7085M	Recombinant Mouse Zfp346 Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Mouse	ZNF346-1782M	Recombinant Mouse ZNF346 Protein (1-294 aa), His-SUMO-tagged	E.coli	His&SUMO	1-294 aa	Inquiry
Mouse	ZNF346-10416M-B	Recombinant Mouse ZNF346 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	ZNF346-10416M	Recombinant Mouse ZNF346 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Zebrafish	ZNF346-5203Z	Recombinant Zebrafish ZNF346	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

ZNF346 involved in several pathways and played different roles in them. We selected most pathways ZNF346 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNF346 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

ZNF346 has several biochemical functions, for example, double-stranded RNA binding, enzyme binding, p53 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZNF346 itself. We selected most functions ZNF346 had, and list some proteins which have the same functions with ZNF346. You can find most of the proteins on our site.

Function	Related Protein
double-stranded RNA binding	IFIH1;LSM14A;TLR7;MYH4;STRBP;DHX58;TLR3;RNASEN;ILF2
enzyme binding	NR5A1;HIF1A;RAD9A;SELS;BCR;HDHD2;HIST1H2AD;RYR2;CYP2A6
p53 binding	USP10;ZFP385C;TRP63;MAPKAPK5;PTTG1IP;RNF20;EP300;CDK5;BRD4
poly(A) RNA binding	APEH;YTHDF2;TDRD9;PWP2;BRIX1;H2-Q10;HSPA9;SERPINH1;FASTKD3
protein binding	NMNAT1;SNRPF;GHRL;FAM46D;HIST1H3A;IPO7;SPRTN;PDCD10;YRDC
zinc ion binding	TRIM40;RORA;RNF113A;SIRT5;NR3C1;RNF217;FHL1A;ZMIZ1A;RNF139

ZNF346 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNF346 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNF346.

TARBP2; EIF2AK2; PB1; NS; NS; ANKHD1; Ccdc9; pre-let-7a; Sod1; NS; Rpl35; THOC2; Klc2; Lima1