ZNF384
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Official Full Name
zinc finger protein 384
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Overview
This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewings sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. -
Synonyms
ZNF384; zinc finger protein 384; TNRC1, trinucleotide repeat containing 1; CAGH1A; CIZ; NMP4; NP; CAG repeat protein 1; expanded repeat domain, CAG/CTG 2; Cas-interacting zinc finger protein; nuclear matrix transcription factor 4; trinucleotide repeat-co;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ZNF384-1501H | Recombinant Human ZNF384 protein, His & T7-tagged | E.coli | His&T7 | Ser307~Pro540 | |
Human | ZNF384-1196H | Recombinant Human ZNF384 Protein (1-245 aa), GST-tagged | E.coli | GST | 1-245 aa | |
Chicken | ZNF384-3535C | Recombinant Chicken ZNF384 | Mammalian Cell | His |
- Other Resource
ZNF384 involved in several pathways and played different roles in them. We selected most pathways ZNF384 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNF384 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ZNF384 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ZNF384 itself. We selected most functions ZNF384 had, and list some proteins which have the same functions with ZNF384. You can find most of the proteins on our site.
Function | Related Protein |
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ZNF384 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNF384 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNF384.
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