Scientists Identified the Special Receptor of Baculovirus for the First Time
Previous studies have identified baculovirus receptors. But recently a report recorded an important finding how baculovirus entered and interacted with human cells. The novel receptor is syndecan- 1 receptor.
The study provides some ideas for the understanding of virus-induced baculovirus infection, and for the future development of therapies. In addition, through the study of the receptor, it helps to reveal the the interaction mechanism between baculovirus and human/mammalian cells, also provides research foundation for clarifying the role of the receptor cells in body.
Baculovirus usually affect insect and they is widely used in the field of biological engineering, for example for the manufacture of glycerol, for the development of cancer vaccines Cervarix and Provenge and others.
Generally, the baculovirus is harmless to human cells, which is why it can be used for gene therapy to treat human diseases; in gene therapy, a variety of methods can be used to correct genetic errors.
Overall, the finding offers us clues to better understand its mechanism and subsequent development.