Cytokines are synthesized and secreted by immune cells and certain non-immune cells. A class of small molecule proteins with a wide range of biological activities. Cytokines generally modulate immune responses by binding to corresponding receptors to regulate cell growth, differentiation and effects. Cytokine (CK) is a low molecular weight soluble protein produced by various cells induced by immunogens, mitogens or other stimulators. It regulates innate and adaptive immunity, hematopoiesis, cell growth, APSC pluripotent cells and damage.
Cytokine (CK) is a low-molecular-weight soluble protein produced by various cells induced by immunogens, mitogens or other stimulators. It regulates innate and adaptive immunity, hematopoiesis, cell growth, and damaged tissue repair. Features. Cytokines can be divided into interleukins, interferons, tumor necrosis factor superfamily, colony stimulating factors, chemokines, growth factors and the like. Numerous cytokines play a role in the body through paracrine, autocrine or endocrine, and have various physiological characteristics such as pleiotropic, overlapping, antagonistic, and synergistic, forming a very complex network of cytokine regulation and participating in many human bodies. An important physiological function.
Cytokines are produced by a variety of cells and have a wide range of functions regulating cell function. Cytokines not only act on the immune system and hematopoietic system, but also on the nervous and endocrine systems, on cell-cell interactions, cell proliferation and differentiation. And the effect function has an important regulatory effect. Cytokines exert a wide variety of biological functions by binding to receptors on the surface of target cell membranes and transmitting signals to the interior of cells. Therefore, understanding the structure and function of cytokine receptors is essential for an in-depth study of the biological functions of cytokines. With the in-depth study of cytokine receptors, it has been found that shared chain phenomena in different subunits of cytokine receptors provide a basis for elucidating the similarities and differences in the biological activities of many cytokines from the receptor level. Most cytokine receptors have soluble forms. Mastering the laws of soluble cytokine receptor production and its physiological and pathological significance will certainly expand people's understanding of the role of cytokine networks. Detection of the levels of cytokines and their receptors has become an important aspect of basic and clinical immunology research.