abi1
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  • Official Full Name
  • abl-interactor 1
  • Background
  • Abelson interactor 1 (ABI1) is widely expressed with highest expression in brain. ABI1 in participation with EPS8 and SOS1?is involved in the transduction of signals from Ras to Rac. At least 10 isoforms are produced by alternative splicing.
  • Synonyms
  • ABI1; abl-interactor 1; spectrin SH3 domain binding protein 1 , SSH3BP1; abl interactor 1; ABI 1; E3B1; Abelson interactor 1; nap1 binding protein; abl-binding protein 4; interactor protein AblBP4; Abl-interactor protein 1 long; eps8 SH3 domain-binding pr
Cat.#:ABI1-085HTag:GST
Source (Host):Wheat Germ (in vitro)Species:Human
Product nameRecombinant Human ABI1 Protein, GST-Tagged
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Cat.#:ABI1-086HTag:GST
Source (Host):Wheat Germ (in vitro)Species:Human
Product nameRecombinant Human ABI1 Protein, GST-Tagged
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Cat.#:ABI1-1704HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ABI1 protein, His & T7-tagged
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Cat.#:ABI1-9246HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ABI1, GST-tagged
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Cat.#:ABI1-3344CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ABI1
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Cat.#:ABI1-9128HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ABI1 293 Cell Lysate
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Cat.#:ABI1-9129HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ABI1 293 Cell Lysate
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Involved Pathway

ABI1 involved in several pathways and played different roles in them. We selected most pathways ABI1 participated on our site, such as E-cadherin signaling in the nascent adherens junction, EGFR1 Signaling Pathway, ErbB1 downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
E-cadherin signaling in the nascent adherens junction
NCKAP1; CTNND1; KLHL20; ABI1; WASF2
EGFR1 Signaling Pathway
RGS5B; RALBP1; PLSCR1; STXBP1A; ZPR1; AP2A1; KRT8; EEF1A1; KRT7; ARF4
ErbB1 downstream signaling
EGR1; BAIAP2; EPS8; ACTR3; CHN2; ACTR2; NCKAP1; WASF2; ARF4; ABI1
Fcgamma receptor (FCGR) dependent phagocytosis
PPAPDC1B; ACTR3; ACTR2B; WIPF2; ABI1A; IgG3; NCKIPSD; ARPC1A; DOCK1; ABI1
Immune System
TRIM41; SIGLEC10; SH3RF1; OSBPL1A; DEFB129; S100B; ASB17; HCST; RNF6; CD300LH
Innate Immune System
ABI1A; TAX1BP1B; DUSP3; CTS7; CLEC4A; NCKIPSD; PELI3; POLR3G; WIPF3; RNF135
RAC1 signaling pathway
NOXA1; ABI1; BAIAP2; NCKAP1; ABI2; NOXO1; IQGAP3; RACGAP1
RHO GTPase Effectors
MKL1; PRC1; DSN1; SPDL1; FMNL1; RTKN; NUF2; ERCC6L; PRC1B; ABI2

Protein Function

ABI1 has several biochemical functions, for example, cytoskeletal protein binding, protein binding, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABI1 itself. We selected most functions ABI1 had, and list some proteins which have the same functions with ABI1. You can find most of the proteins on our site.
Function
Related Protein
Function cytoskeletal protein binding
Related Protein CAPN1; PACSIN1A; EPB41L4B; ABI1; CORO1A; EZRA; DYNLL2; TPM1; RPH3AL; EPB41L5
Function protein binding
Related Protein PDCD2; Txn1; DRAXIN; FBXO33; RAB9A; DSTN; PPP2R5C; MRPL11; ING1; SNX15
Function protein complex binding
Related Protein RIPK3; LRP1; CRHR1; RIPK1; CALCA; Cel; MYC; CYFIP1; FBLN1; ATM
Function protein tyrosine kinase activator activity
Related Protein ERBB3; CD24; AFAP1L2; GAS6; ABI1; ERCC6; ABI1A; ABI3A; NRG1; ABI1B

Interacting Protein

ABI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABI1.
ABL1; NCKAP1; WASF2