Recombinant Human ABI1 Protein, GST-Tagged ABI1-086H

Recombinant Human ABI1 Protein, GST-Tagged

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Recombinant Human ABI1 Protein, GST-Tagged

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Cat.No. : ABI1-086H
Product Overview : Human ABI1 partial ORF ( NP_001012770, 185 a.a. - 238 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 31.68 kDa
AA Sequence : GTLGRNTPYK TLEPVKPPTV PNDYMTSPAR LGSQHSPGRT ASLNQRPRTH SGSS
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Figure :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : ABI1 abl-interactor 1 [ Homo sapiens ]
Official Symbol : ABI1
Synonyms : ABI1; abl-interactor 1; spectrin SH3 domain binding protein 1 , SSH3BP1; abl interactor 1; ABI 1; E3B1; Abelson interactor 1; nap1 binding protein; abl-binding protein 4; interactor protein AblBP4; Abl-interactor protein 1 long; eps8 SH3 domain-binding protein; spectrin SH3 domain-binding protein 1; ABI-1; ABLBP4; NAP1BP; SSH3BP; SSH3BP1;
Gene ID : 10006
mRNA Refseq : NM_001012750
Protein Refseq : NP_001012768
MIM : 603050
UniProt ID : Q8IZP0
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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