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Recombinant Human ABI1 Protein, GST-Tagged

Cat.No. : ABI1-086H
Product Overview : Human ABI1 partial ORF ( NP_001012770, 185 a.a. - 238 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 31.68 kDa
AA Sequence : GTLGRNTPYKTLEPVKPPTVPNDYM TSPARLGSQHSPGRTASLNQRPRTH SGSS
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ABI1 abl-interactor 1 [ Homo sapiens ]
Official Symbol : ABI1
Synonyms : ABI1; abl-interactor 1; spectrin SH3 domain binding protein 1 , SSH3BP1; abl interactor 1; ABI 1; E3B1; Abelson interactor 1; nap1 binding protein; abl-binding protein 4; interactor protein AblBP4; Abl-interactor protein 1 long; eps8 SH3 domain-binding protein; spectrin SH3 domain-binding protein 1; ABI-1; ABLBP4; NAP1BP; SSH3BP; SSH3BP1;
Gene ID : 10006
mRNA Refseq : NM_001012750
Protein Refseq : NP_001012768
MIM : 603050
UniProt ID : Q8IZP0

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Is there a TEV cleavage site between the GST tag and the ABI1 protein sequence? 04/14/2023

Some of our products contain cleavage sites between the tag and the target protein. Please consult our experts for specific product information.

Can you express the ABI1 fusion protein with MBP tag? 04/14/2023

Sure, Creative BioMart supports custom protein production services.

Which expression systems does recombinant ABI1 protein use? 04/14/2023

We provide various expression systems, including E. coli, wheat germ, in vitro cell free system, and mammalian cell expression systems.

What signaling pathway is ABI1 involved in? 04/14/2023

ABI1 may play a role in regulating EGF-induced activation of the Erk pathway and, together with EPS8, is involved in signal transduction from Ras to Rac.

Can your ABI1 proteins be used for WB? 04/14/2023

Yes, our recombinant ABI1 protein can be used as a variety of applications based on the antigen-antibody reaction.

Customer Reviews (2)

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Reviews
06/14/2020

    Recombinant chicken ABI1 has high purity and good immunogenicity, and the experimental results are very satisfactory.

    05/13/2018

      The technical support experts at Creative BioMart customized the ABI1 protein with a specific expression system and fusion tag for me.

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