|Official Full Name||amiloride-sensitive cation channel 2, neuronal|
|Background||This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown. Alternative splicing of this gene generates 2 transcript products.|
|Synonyms||ACCN2; amiloride-sensitive cation channel 2, neuronal; ASIC1; BNaC2; hBNaC2; neuronal; ACCN2_HUMAN; Acid sensing ion channel 1; Acid sensing ion channel 1a protein; Acid sensing ion channel; Acid-sensing ion channel 1; AI843610; Amiloride sensitive cation channel 2 neuronal; Amiloride-sensitive cation channel 2; ASIC; ASIC1A; B530003N02Rik; Brain sodium channel 2; Cation channel amiloride sensitive neuronal 2; ACCN2 variant 3; acid-sensing ion channel 1a protein; Cation channel, amiloride-sensitive, neuronal, 2|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ACCN2 involved in several pathways and played different roles in them. We selected most pathways ACCN2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ACCN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
ACCN2 has several biochemical functions, for example, acid-sensing ion channel activity, ion gated channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACCN2 itself. We selected most functions ACCN2 had, and list some proteins which have the same functions with ACCN2. You can find most of the proteins on our site.
|acid-sensing ion channel activity||ASIC1; ASIC1C; ACCN2; ASIC1B; ASIC1A|
|ion gated channel activity||ACCN2; ASIC1|
ACCN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACCN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACCN2.