ACSBG1
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Official Full Name
acyl-CoA synthetase bubblegum family member 1
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
ACSBG1 involved in several pathways and played different roles in them. We selected most pathways ACSBG1 participated on our site, such as Fatty acid biosynthesis, Fatty acid degradation, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACSBG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fatty acid biosynthesis | ACSL1B;ACSL4A;DECR1;ACSBG1;ACSL4;FASN;ECHDC2;ACSL4B;ACSL5 |
| Fatty acid degradation | ACADS;ADH1C;ACSBG2;CYP4A12A;CPT1B;ACAA1;ALDH9A1B;ADH1A;ACSL5 |
| Metabolic pathways | PNMT;LDHAL6A;CYP3A41A;PCYT2;XDH;ALDOAA;EXT1B;GALE;HPSE |
| Fatty acid metabolism | HADHA;ACACA;HADHB;PECR;ACAA1;ACAT2;HADH;ELOVL2;HSD17B12B |
| PPAR signaling pathway | APOA2;ACSL1B;ACSL4A;PPARG;PPARDB;APOA1;ACOX1;ACSL3A;FABP1A |
| Adipocytokine signaling pathway | CHUK;TNFRSF1B;RELA;PRKAG2;NFKBIAA;ACSL4B;PTPN11A;LEPA;POMC |
ACSBG1 has several biochemical functions, for example, ATP binding, long-chain fatty acid-CoA ligase activity, very long-chain fatty acid-CoA ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACSBG1 itself. We selected most functions ACSBG1 had, and list some proteins which have the same functions with ACSBG1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | FKBP4;TOR1A;HSPA4B;TP53RK;KDRL;STK24B;P2RX6;MYO1D;CLP1 |
| long-chain fatty acid-CoA ligase activity | SLC27A3;SLC27A4;ACSL3;SLC27A2;ACSBG2;ACSL1;ACSL4;SLC27A1A;ACSL5 |
| very long-chain fatty acid-CoA ligase activity | ACSBG1;SLC27A3;SLC27A1B;ACSL4;SLC27A4;SLC27A1A;SLC27A2;SLC27A5 |
ACSBG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACSBG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACSBG1.
GSK3B
- Q&As
- Reviews
Q&As (10)
Ask a questionACSBG1 knockout in animal models leads to improved insulin sensitivity, and ACSBG1 expression is upregulated in insulin-resistant states.
ACSBG1 is primarily expressed in the liver and adipose tissue, but is also found in other tissues such as the brain.
ACSBG1 is involved in insulin signaling by regulating the levels of diacylglycerols, which can activate PKCε and inhibit insulin signaling.
PGC-1α regulates ACSBG1 expression by interacting with PPARα to increase transcription, as well as by promoting the acetylation of histones in the ACSBG1 promoter region.
ACSBG1 has been found to be upregulated in several types of cancer, including breast, prostate, and liver cancer, and may play a role in tumor growth and progression.
ACSBG1 is involved in the formation of lipid droplets by promoting the esterification of fatty acids into triacylglycerols.
ACSBG1 expression is regulated by a number of transcription factors, including SREBP1c, PPARα, and PGC-1α, which are all involved in regulating lipid metabolism.
ACSBG1 expression is upregulated in the liver of individuals with NAFLD, and ACSBG1 knockout in animal models leads to reduced hepatic steatosis.
PPARα regulates ACSBG1 expression by binding to a specific site in the ACSBG1 promoter and increasing transcription.
ACSBG1 has a broad substrate specificity and can activate a variety of long-chain fatty acids.
Customer Reviews (5)
Write a reviewThe samples provided by the manufacturer allowed me to test out different proteins before committing to a larger purchase, which was extremely helpful.
The manufacturer's consistency in delivering high quality proteins has made them my go-to supplier.
I was impressed by the follow-up from the manufacturer's after-sales team, who ensured that I was satisfied with my purchase.
A satisfying purchase
All good. Will recommand to my other colleague
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