ADCY8 Protein, adenylate cyclase 8 (brain)


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Official Full Name adenylate cyclase 8 (brain)
Background Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic;activity is under the control of several hormones, and different polypeptides participate in the transduction of the;signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G;proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the;adenylyl cyclase.
Synonyms ADCY8; adenylate cyclase 8 (brain); ADCY3; adenylate cyclase type 8; AC8; HBAC1; adenylyl cyclase 8; ATP pyrophosphate-lyase 8; adenylyl cyclase-8, brain; adenylate cyclase type VIII; ca(2+)/calmodulin-activated adenylyl cyclase
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADCY8-136H Recombinant Human ADCY8 Mammalian Cell His
    Human ADCY8-3182H Recombinant Human ADCY8, His-tagged E.Coli or Yeast His
    Human ADCY8-332H Recombinant Human ADCY8 Protein, GST-tagged Wheat Germ GST
    Human ADCY8-6934H Recombinant Human ADCY8 protein, His & GST-tagged E.coli His/GST
    Human ADCY8-9020HCL Recombinant Human ADCY8 293 Cell Lysate HEK293 N/A
    Mouse ADCY8-1346M Recombinant Mouse ADCY8 Protein Mammalian Cell His
    Mouse Adcy8-3181M Recombinant Mouse Adcy8, His-tagged E.Coli or Yeast His
    Rat ADCY8-519R Recombinant Rat ADCY8 Protein Mammalian Cell His
    Zebrafish ADCY8-7257Z Recombinant Zebrafish ADCY8 Mammalian Cell His

    ADCY8 involved in several pathways and played different roles in them. We selected most pathways ADCY8 participated on our site, such as Activation of GABAB receptors, Activation of NMDA receptor upon glutamate binding and postsynaptic events, Adenylate cyclase activating pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADCY8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of GABAB receptors KCNJ15; KCNJ5; ADCY1; ADCY9; ADCY3; ADCY7; ADCY8; GNB3B; GNB3A; KCNJ6
    Activation of NMDA receptor upon glutamate binding and postsynaptic events CAMKK1B; DLG4; PDPK1A; ADCY1; ADCY8; NETO2; NEFLB; CREB1; SLC14A2; ADCY3
    Adenylate cyclase activating pathway ADCY3; ADCY8; ADCY1; ADCY6; ADCY9; ADCY7
    Adenylate cyclase inhibitory pathway ADCY7; ADCY6; ADCY1; ADCY9; ADCY3; ADCY8
    Adrenergic signaling in cardiomyocytes TNNC1A; ADRA1B; PPP2R5A; CACNA2D1; PRKACA; ATP1B3A; PIK3R5; CACNG6; TPM4; MYH15
    Aldosterone synthesis and secretion NETO2; ATF1; PLCB3; CAMK2D; GNAS; PRKACA; KCNK9; GNA11; CAMK1D; ATF2
    Aquaporin-mediated transport AQP10A; ADCY6; AQP11; GNB5B; AQP9B; GNB3B; MYO5B; AQP8A.1; ADCY9; ADCY1
    Bile secretion SLCO1B2; ATP1A3; ATP1A1; SLC9A1; SCTR; NCEH1; SLC22A1; ABCB11; SLC10A2; OSTA

    ADCY8 has several biochemical functions, for example, ATP binding, adenylate cyclase activity, calcium- and calmodulin-responsive adenylate cyclase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADCY8 itself. We selected most functions ADCY8 had, and list some proteins which have the same functions with ADCY8. You can find most of the proteins on our site.

    Function Related Protein
    adenylate cyclase activity ADCY3; ADCY1B; GNAS; ADCY8; ADCY6; ADCY2B; ADCY9; ADCY1; Adcy4; ADCY1A
    calcium- and calmodulin-responsive adenylate cyclase activity ADCY3; ADCY1; ADCY8; ADCY6
    metal ion binding ABLIM1A; ADAP1; COL1A2; ZFP830; POLI; PDE7B; S100T; PRIM1; SOBPA; ITGA8

    ADCY8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADCY8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADCY8.


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