Recombinant Human ADCY8 protein, His & GST-tagged

• Cat.No.: ADCY8-6934H
• Product Overview: Recombinant Human ADCY8 aa. (Lys234~Glu371 (Accession # P40145)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Lys234~Glu371
• Description: Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 45.3kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 8.0.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: ADCY8 adenylate cyclase 8 [ Homo sapiens (human) ]
• Official Symbol: ADCY8
• Synonyms: ADCY8; adenylate cyclase 8; AC8; ADCY3; HBAC1; adenylate cyclase type 8; ATP pyrophosphate-lyase 8; HEL-S-172mP; adenylate cyclase 8 (brain); adenylate cyclase type VIII; adenylyl cyclase 8; adenylyl cyclase-8, brain; ca(2+)/calmodulin-activated adenylyl cyclase; epididymis secretory sperm binding protein Li 172mP
• Gene ID: 114
• mRNA Refseq: NM_001115.2
• Protein Refseq: NP_001106.1
• UniProt ID: P40145