adi1
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  • Official Full Name
  • acireductone dioxygenase 1
  • Background
  • This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20.
  • Synonyms
  • ADI1; acireductone dioxygenase 1; 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; APL1; ARD; FLJ10913; HMFT1638; membrane type 1 matrix metalloproteinase cytoplasmic tail binding protein 1; MTCBP 1; SIPL; 1; 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Aci reductone dioxygenase; Acireductone dioxygenase (Ni(2+)-requiring); ADI 1; anti ADI1; EC 1.13.; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; MTCBP-1; MTCBP1; MTND_HUMAN; Ni-ARD; Submergence induced protein 2 homolog; Submergence-induced protein 2 homolog; submergence induced protein 2; MT1-MMP cytoplasmic tail-binding protein-1; membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1
Cat.#:ADI1-27097THTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADI1, T7 -tagged
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Cat.#:ADI1-392HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Acireductone Dioxygenase 1, T7-tagged
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Cat.#:ADI1-165HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADI1 protein, T7-tagged
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Cat.#:ADI1-357HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ADI1 Protein, GST-tagged
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Cat.#:ADI1-7531HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADI1, His-tagged
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Cat.#:ADI1-9423HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADI1, GST-tagged
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Cat.#:ADI1-1359MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ADI1 Protein
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Cat.#:ADI1-528RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ADI1 Protein
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Cat.#:ADI1-2764CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ADI1
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Cat.#:ADI1-10067ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ADI1
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Cat.#:ADI1-9011HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ADI1 293 Cell Lysate
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Involved Pathway

ADI1 involved in several pathways and played different roles in them. We selected most pathways ADI1 participated on our site, such as Cysteine and methionine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cysteine and methionine metabolism
LDHC; LDHBA; AGXT2; GOT2; APIP; AHCY; ADI1; IL4I1; AHCYL1; GCLM
Metabolic pathways
POLR2J3; CYP11B2; ADH2-1; FUT6; Nat3; DAD1; ATP5O; AGMAT; DGUOK; NT5C1B

Protein Function

ADI1 has several biochemical functions, for example, acireductone dioxygenase [iron(II)-requiring] activity, metal ion binding, oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADI1 itself. We selected most functions ADI1 had, and list some proteins which have the same functions with ADI1. You can find most of the proteins on our site.
Function
Related Protein
Function acireductone dioxygenase [iron(II)-requiring] activity
Related Protein ADI1
Function metal ion binding
Related Protein TMEM129; TRIM30A; FAHD1; COL5A2; RXRGA; KCND3; ZNF80; ANKIB1; CYP2AD3; ZNF776
Function oxidoreductase activity
Related Protein NDOR1; HPDA; CYP2K6; RNLS; ALOX5B.3; GPX4B; HIBADHB; HIBADHA; LDHBA; GPX5
Function protein binding
Related Protein TAGLN2; FOXJ2; PLXNC1; SH3GL1; BIN3; FGA; KLF6; DDRGK1; HSPA9; C10orf33

Interacting Protein

ADI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADI1.
MMP14; SRPK1; DBT; OSTF1

ADI1 Related Articles

Valdez, CE; Smith, QA; et al. Mysteries of Metals in Metalloenzymes. ACCOUNTS OF CHEMICAL RESEARCH 47:3110-3117(2014).
Allpress, CJ; Berreau, LM; et al. A Nickel-Containing Model System of Acireductone Dioxygenases that Utilizes a C(1)-H Acireductone Substrate. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY :4642-4649(2014).