ADRBK1 Protein, adrenergic, beta, receptor kinase 1


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Official Full Name adrenergic, beta, receptor kinase 1
Background G-protein-coupled receptor kinase 2 (GRK2), also known as beta-adrenergic receptor kinase 1 (beta-ARK1), is a member of the GRK family, which phosphorylates the activated form of G-protein-coupled receptors (GPCRs) and initiates the desensitization proces
Synonyms ADRBK1; adrenergic, beta, receptor kinase 1; beta-adrenergic receptor kinase 1; BARK1; GRK2; beta-ARK-1; G-protein coupled receptor kinase 2; BETA-ARK1; FLJ16718
    • Species :
    • Chicken
    • Human
    • Rat
    • Source :
    • E.coli
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADRBK1-1019H Recombinant Human Adrenergic, Beta, Receptor Kinase 1, GST-tagged Sf9 Insect Cell GST
    Human ADRBK1-152H Recombinant Human ADRBK1 Mammalian Cell His
    Human ADRBK1-357H Recombinant Human Adrenergic, Beta, Receptor Kinase 1, His-tagged Insect Cell His
    Human ADRBK1-383H Recombinant Human ADRBK1 Protein, GST-tagged Insect Cell GST
    Human ADRBK1-625HCL Recombinant Human ADRBK1 cell lysate Insect Cell N/A
    Human ADRBK1-9445H Recombinant Human ADRBK1, His-tagged E.coli His
    Human ADRBK1-978H Recombinant Human ADRBK1, His & GST tagged Insect Cell His/GST
    Rat ADRBK1-546R Recombinant Rat ADRBK1 Protein Mammalian Cell His
    Chicken ADRBK1-3006C Recombinant Chicken ADRBK1 Mammalian Cell His

    ADRBK1 involved in several pathways and played different roles in them. We selected most pathways ADRBK1 participated on our site, such as Activation of SMO, CXCR4-mediated signaling events, Ca-dependent events, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADRBK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of SMO BOC; KIF3A; CSNK1A1; SETD6; IQCE; ADRBK1; EVC2; EFCAB7; CDON; GAS8
    CXCR4-mediated signaling events GNB2L1; GNA13; MAPKAP1; PAG1; CFL1; DNM1; ADRBK1; BLK; JAK2; ARR3
    Ca-dependent events ADCY9; PRKAR1AA; ADCY7; ADRBK1
    CaM pathway PRKAR1AA; ADRBK1
    Calmodulin induced events PRKAR1AA; ADRBK1
    Chemokine signaling pathway CCL22; PF4V1; GNG4; KRAS; CCL8; GNB3; RHOA; HCK; AKT2; CX3CR1
    DAG and IP3 signaling ADRBK1; AHCYL1; PRKAR1AA
    DAP12 interactions FGF8B; TREM1; SPNA1; IL17RD; DUSP6; SPTBN1; DUSP10; AHCYL1; JAK3; KLB

    ADRBK1 has several biochemical functions, for example, ATP binding, Edg-2 lysophosphatidic acid receptor binding, G-protein coupled receptor kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADRBK1 itself. We selected most functions ADRBK1 had, and list some proteins which have the same functions with ADRBK1. You can find most of the proteins on our site.

    Function Related Protein
    Edg-2 lysophosphatidic acid receptor binding ADRBK1
    G-protein coupled receptor kinase activity GRK7A; GRK4; ADRBK2; GRK7; GRK1; GRK7B; RLN1; GRK6; ADRBK1; GRK1A
    alpha-2A adrenergic receptor binding UCHL1; ADRBK1; ADRB1; ADRA2C; APLP1
    beta-adrenergic receptor kinase activity GRK6; ADRBK1; ADRBK2; GRK5
    protein binding HIST2H4; ZNF543; TACSTD2; HNRNPH3; TRAM1; RPLP0; SNX7; BTC; CARTPT; NLRC5
    protein kinase activity MKNK2B; PIK3R4; ABL2; MAK; GUCY2C; GC3; AKT1; RPS6KA5; STK24A; PDK2

    ADRBK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADRBK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADRBK1.


    Wex, E; Thaler, E; et al. A Novel Model of IgE-Mediated Passive Pulmonary Anaphylaxis in Rats. PLOS ONE 9:-(2014).
    Hartung, JE; Ciszek, BP; et al. beta(2)- and beta(3)-adrenergic receptors drive COMT-dependent pain by increasing production of nitric oxide and cytokines. PAIN 155:1346-1355(2014).

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