• Official Full Name
  • ArfGAP with FG repeats 1
  • Background
  • The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • AGFG1; ArfGAP with FG repeats 1; HIV 1 Rev binding protein , HRB; arf-GAP domain and FG repeats-containing protein 1; RAB; RIP; D730048C23Rik; HIV 1 Rev binding protein; MGC116375; MGC116938; MGC116940; Rev/Rex activation domain-binding protein; AGFG1_HUMAN; AU045498; C130049H11Rik; C85612; DKFZp686I15205; HIV-1 Rev-binding protein; HRB; Nucleoporin like protein RIP; Nucleoporin-like protein RIP; Rev interacting protein; Rev-interacting protein; HIV-1 Rev binding protein; hRIP, Rev interacting protein; Rab, Rev/Rex activation domain-binding protein
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human AGFG1 Protein, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AGFG1 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human AGFG1, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse AGFG1 Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat AGFG1 Protein
Source (Host):Species:Human
Product nameRecombinant Human AGFG1 293 Cell Lysate

Involved Pathway

AGFG1 involved in several pathways and played different roles in them. We selected most pathways AGFG1 participated on our site, such as Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with AGFG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Influenza A
BMA1; ACTG1; LOC100033925; EIF2AK1; NLRX1; PRKCA; H2-AA; NXF1; HSPA2; MAPK12

Protein Function

AGFG1 has several biochemical functions, for example, DNA binding, GTPase activator activity, RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AGFG1 itself. We selected most functions AGFG1 had, and list some proteins which have the same functions with AGFG1. You can find most of the proteins on our site.
Related Protein
Function DNA binding
Related Protein THAP4; SOX15; ZNF529; Trl; ONECUT1; SYCP1; POLR3B; NAT14; ERCC6L; HIST1H47
Function GTPase activator activity
Related Protein VPS9D1; SRGAP3; THY1; GRTP1; TBC1D10A; RANGAP1; HTR2B; RGS14A; AXIN1; ARHGAP26
Function RNA binding
Related Protein PABPC1L2A; EIF4E3; NOL9; PCBP1; CAPRIN1; RPS15A; CELF5; NOM1; RBM23; RPL7A
Function metal ion binding
Related Protein ZFP451; SLC25A25A; DYTN; KLF5; MOXD1L; ZC3HAV1; RAB11FIP4A; PCGF5A; ZC3H10; ELMSAN1A
Function protein binding
Related Protein WBP2; DSG1A; ARRB1; GTF3C5; GPRC5A; UBXN1; TPD52L2; PPP2R5A; ZFC3H1; RNF138

Interacting Protein

AGFG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGFG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AGFG1.