AKAP8 Protein, A kinase (PRKA) anchor protein 8


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Official Full Name A kinase (PRKA) anchor protein 8
Background This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9.
Synonyms AKAP8; A kinase (PRKA) anchor protein 8; A-kinase anchor protein 8; A kinase anchor protein; 95kDa; AKAP95; DKFZp586B1222; A-kinase anchor protein, 95kDa; AKAP-8; AKAP 95; AKAP-95
    • Species :
    • Human
    • Source :
    • E.Coli or Yeast
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human AKAP8-3032H Recombinant Human AKAP8, His-tagged E.Coli or Yeast His
    Human AKAP8-403H Recombinant Human AKAP8 Protein, GST-tagged Wheat Germ GST
    Human AKAP8-46HCL Recombinant Human AKAP8 cell lysate N/A

    AKAP8 involved in several pathways and played different roles in them. We selected most pathways AKAP8 participated on our site, such as G Protein Signaling Pathways, TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with AKAP8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    G Protein Signaling Pathways AKAP5; Akap2; AKAP8; ARHGEF1A; KCNJ3; AKAP12; GNG13B; AKAP10; AKAP6; GNB3B
    TNF-alpha/NF-kB Signaling Pathway ZFAND5; RNF216; PDCD2; CSNK2A1P; AKAP8; COMMD1; NR2C2; PPP1R13L; DDX3X; DPF2

    AKAP8 has several biochemical functions, for example, double-stranded DNA binding, poly(A) RNA binding, protein kinase A regulatory subunit binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AKAP8 itself. We selected most functions AKAP8 had, and list some proteins which have the same functions with AKAP8. You can find most of the proteins on our site.

    Function Related Protein
    double-stranded DNA binding TP73; TEF; FBXO18; XRCC3; ERCC5; SP1; MEN1; NEIL3; MCM10; PIN4
    poly(A) RNA binding SRP68; DCD; ANP32A; USP10; PDIA3; TRA2B; HMGN2; SUMO2; WDR3; DDX28
    protein kinase A regulatory subunit binding C2orf88; RYR2; ARFGEF2; AKAP1; AKAP7; ACBD3; KCNQ1; AKAP9; EZR; AKAP5
    zinc ion binding ADAM30; NR5A1; ZFYVE20; BRAP; MKRN1; PRKCA; VDRB; RNF181; SRSF7; CPA4

    AKAP8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AKAP8 here. Most of them are supplied by our site. Hope this information will be useful for your research of AKAP8.

    MYC; ESR1; CSNK2A1; Aurkb; Mis12; SCHIP1; ssrna_ug; E2F3; HNRNPA1; MATR3; YBX1; ILK; LRRK2; HIPK4; ESR2; HDAC11

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