Recombinant Human AKAP8 cell lysate

• Cat.No.: AKAP8-46HCL

Specification

• Species: Human
• Tag: Non
• Description: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is located in the nucleus during interphase and is distinctly redistributed during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: AKAP8 A kinase (PRKA) anchor protein 8 [ Homo sapiens ]
• Official Symbol: AKAP8
• Synonyms: AKAP8; A kinase (PRKA) anchor protein 8; A-kinase anchor protein 8; A kinase anchor protein; 95kDa; AKAP95; DKFZp586B1222; A-kinase anchor protein, 95kDa; AKAP-8; AKAP 95; AKAP-95
• Gene ID: 10270
• mRNA Refseq: NM_005858
• Protein Refseq: NP_005849
• MIM: 604692
• UniProt ID: O43823
• Chromosome Location: 19p13.1-q12
• Pathway: G Protein Signaling Pathways, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem
• Function: DNA binding; double-stranded DNA binding; metal ion binding; protein kinase A regulatory subunit binding; zinc ion binding