Recombinant Human AKAP8 Protein, GST-tagged

• Cat.No.: AKAP8-403H
• Product Overview: Human AKAP8 full-length ORF ( AAH37270.1, 1 a.a. - 692 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 102.6 kDa
• AA Sequence: MDQGYGGYGAWSAGPANTQGAYGTG VASWQGYENYNYYGAQNTSVTTGAT YSYGPASWEAAKANDGGLAAGAPAM HMASYGPEPCTDNSDSLIAKINQRL DMMSKEGGRGGSDGGGEGIQDRESS FRFQPFESYDSRPCLPEHNPYRPSY SYDYEFDLGSDRNGSFGGQYSECRD PARERGSLDGFMRGRGQGRFQDRSN PGTFMRSDPFVPPAASSEPLSTPWN ELNYVGGRGLGGPSPSRPPPSLFSQ SMAPDYGVMGMQGAGGYDSTMPYGC GRSQPRMRDRDRPKRRGFDRFGPDG TGRKRKQFQLYEEPDTKLARVDSEG DFSENDDAAGDFRSGDEEFKGEDEL CDSGRQRGEKEDEDEDVKKRREKQR RRDRTRDRAADRIQFACSVCKFRSF DDEEIQKHLQSKFHKETLRFISTKL PDKTVEFLQEYIVNRNKKIEKRRQE LMEKETAKPKPDPFKGIGQEHFFKK IEAAHCLACDMLIPAQPQLLQRHLH SVDHNHNRRLAAEQFKKTSLHVAKS VLNNRHIVKMLEKYLKGEDPFTSET VDPEMEGDDNLGGEDKKETPEEVAA DVLAEVITAAVRAVDGEGAPAPESS GEPAEDEGPTDTAEAGSDPQAEQLL EEQVPCGTAHEKGVPKARSEAAEAG NGAETMAAEAESAQTRVAPAPAAAD AEVEQTDAESKDAVPTE
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AKAP8 A kinase (PRKA) anchor protein 8 [ Homo sapiens ]
• Official Symbol: AKAP8
• Synonyms: AKAP8; A kinase (PRKA) anchor protein 8; A-kinase anchor protein 8; A kinase anchor protein; 95kDa; AKAP95; DKFZp586B1222; A-kinase anchor protein, 95kDa; AKAP-8; AKAP 95; AKAP-95
• Gene ID: 10270
• mRNA Refseq: NM_005858
• Protein Refseq: NP_005849
• MIM: 604692
• UniProt ID: O43823