alx1
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  • Official Full Name
  • ALX homeobox 1
  • Background
  • The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for;survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse;gene lead to neural tube defects such as acrania and meroanencephaly.
  • Synonyms
  • ALX1; ALX homeobox 1; CART1, cartilage paired class homeoprotein 1; ALX homeobox protein 1; ALX1_HUMAN; CART 1; CART-1; CART1; Cartilage homeoprotein 1; OTTHUMP00000242207; cartilage paired-class homeoprotein 1; FND3
Cat.#:ALX1-0012HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ALX1 Protein, GST-Tagged
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Cat.#:ALX1-037HTag:GST/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ALX1 Protein, GST-HIS-tagged
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Cat.#:ALX1-9604HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ALX1, His-tagged
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Cat.#:ALX1-1581MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ALX1 Protein
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Cat.#:ALX1-4127ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ALX1
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Cat.#:ALX1-8890HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ALX1 293 Cell Lysate
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Protein Function

ALX1 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALX1 itself. We selected most functions ALX1 had, and list some proteins which have the same functions with ALX1. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II regulatory region sequence-specific DNA binding
Related Protein SP5; SKINT8; ZNF549; RARG; GATA1; MNT; BCL6A; GLIS1; NFKB1; EAF2
Function protein binding
Related Protein LAGE3; WFDC9; TRIM25; MLL1; TRAPPC6A; AXIN2; CBY1; KCNQ5; Tnfrsf23; SSNA1
Function protein heterodimerization activity
Related Protein ITGB1A; HIST1H3F; CYBB; UGT1A2; OSTB; SYCP3; HEXB; PIK3R2; H2AFB3; HIST1H2AF
Function protein homodimerization activity
Related Protein STK4; MSH2; SLC14A2; ABCG1; MVD; NDP; UGT1A3; UGT1A6B; EIF2AK3; TCF12
Function transcription corepressor activity
Related Protein ZNF593; NAB2; HOMEZA; HDAC5; ZEB1; PROX1; PFDN5; KCNIP3; TBL1XR1B; E2F6
Function transcription factor activity, sequence-specific DNA binding
Related Protein ZNF584; RFXANK; TP53; SCML2; NANOG; SNAPC4; SIX1B; IRF4; SALL3; ZFP639
Function transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
Related Protein GRHL2; BARX2; GATA4; DMRT1; NR1I2; MYOCD; HIF1A; NR1I3; GATA3; GATA1A

Interacting Protein

ALX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALX1.
IPO13