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Official Full Name ALX homeobox 1
Background The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for;survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse;gene lead to neural tube defects such as acrania and meroanencephaly.
Synonyms ALX1; ALX homeobox 1; CART1, cartilage paired class homeoprotein 1; ALX homeobox protein 1; ALX1_HUMAN; CART 1; CART-1; CART1; Cartilage homeoprotein 1; OTTHUMP00000242207; cartilage paired-class homeoprotein 1; FND3
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ALX1-0012H Recombinant Human ALX1 Protein, GST-Tagged Wheat Germ GST
    Human ALX1-037H Recombinant Human ALX1 Protein, GST-HIS-tagged E.coli GST/His
    Human ALX1-8890HCL Recombinant Human ALX1 293 Cell Lysate HEK293 N/A
    Human ALX1-9604H Recombinant Human ALX1, His-tagged E.coli His
    Mouse ALX1-1581M Recombinant Mouse ALX1 Protein Mammalian Cell His
    Zebrafish ALX1-4127Z Recombinant Zebrafish ALX1 Mammalian Cell His

    ALX1 involved in several pathways and played different roles in them. We selected most pathways ALX1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ALX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    ALX1 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALX1 itself. We selected most functions ALX1 had, and list some proteins which have the same functions with ALX1. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II regulatory region sequence-specific DNA binding SP1; ZNF691; ARHGAP35; ZBTB16A; ATF5; ETV6; FOXD3; FERD3L; NHLH1; STAT4
    protein binding BLOC1S2A; ZSCAN12; PRKD2; SERPINE2; RNF144B; ARFGAP1; TXNDC16; DRAP1; DNMT3A; ARHGEF38
    protein heterodimerization activity CXorf15; SDCBP2; GRIN1; BMP7A; HIST1H2BH; UGT1A7; EGFR; MAFA; JAM2A; P4HB
    protein homodimerization activity STC2; SYNDIG1; RELA; KLHL7; SDS; APOA1BP; SLC22A6; VPS25; QDPR; TPD52L1
    transcription corepressor activity C1QBP; SKIL; ATF5; TBL1XR1A; GMNN; SIAH2; CTBP2; MXI1; CTBP2A; ZHX2
    transcription factor activity, sequence-specific DNA binding CRX; NR5A1A; FOSL1; TULP4; RB1; ZNF239; RFX3; PDX1; FOXN2; IRF3
    transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding BARHL1A; GRHL2; FOXC1; GATA3; ARID3A; CSRNP3; BARX1; GRHL3; FOXO3; IKZF3

    ALX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALX1.


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