|Official Full Name||ALX homeobox 1|
|Background||The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for;survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse;gene lead to neural tube defects such as acrania and meroanencephaly.|
|Synonyms||ALX1; ALX homeobox 1; CART1, cartilage paired class homeoprotein 1; ALX homeobox protein 1; ALX1_HUMAN; CART 1; CART-1; CART1; Cartilage homeoprotein 1; OTTHUMP00000242207; cartilage paired-class homeoprotein 1; FND3|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ALX1 involved in several pathways and played different roles in them. We selected most pathways ALX1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ALX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
ALX1 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALX1 itself. We selected most functions ALX1 had, and list some proteins which have the same functions with ALX1. You can find most of the proteins on our site.
|RNA polymerase II regulatory region sequence-specific DNA binding||SP1; ZNF691; ARHGAP35; ZBTB16A; ATF5; ETV6; FOXD3; FERD3L; NHLH1; STAT4|
|protein binding||BLOC1S2A; ZSCAN12; PRKD2; SERPINE2; RNF144B; ARFGAP1; TXNDC16; DRAP1; DNMT3A; ARHGEF38|
|protein heterodimerization activity||CXorf15; SDCBP2; GRIN1; BMP7A; HIST1H2BH; UGT1A7; EGFR; MAFA; JAM2A; P4HB|
|protein homodimerization activity||STC2; SYNDIG1; RELA; KLHL7; SDS; APOA1BP; SLC22A6; VPS25; QDPR; TPD52L1|
|transcription corepressor activity||C1QBP; SKIL; ATF5; TBL1XR1A; GMNN; SIAH2; CTBP2; MXI1; CTBP2A; ZHX2|
|transcription factor activity, sequence-specific DNA binding||CRX; NR5A1A; FOSL1; TULP4; RB1; ZNF239; RFX3; PDX1; FOXN2; IRF3|
|transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding||BARHL1A; GRHL2; FOXC1; GATA3; ARID3A; CSRNP3; BARX1; GRHL3; FOXO3; IKZF3|
ALX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALX1.