amn
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  • Official Full Name
  • amnionless homolog (mouse)
  • Background
  • The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila.
  • Synonyms
  • AMN; amnionless homolog (mouse); protein amnionless; visceral endoderm-specific type 1 transmembrane protein; PRO1028
Cat.#:AMN-1987HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human AMN Protein, MYC/DDK-tagged
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Cat.#:AMN-7084HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AMN, His-tagged
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Cat.#:AMN-768HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human AMN
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Cat.#:AMN-777HTag:His
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human AMN Protein, His-tagged
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Cat.#:AMN-4907CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken AMN
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Involved Pathway

AMN involved in several pathways and played different roles in them. We selected most pathways AMN participated on our site, such as Cobalamin (Cbl, vitamin B12) transport and metabolism, Defective AMN causes hereditary megaloblastic anemia 1, Defective CUBN causes hereditary megaloblastic anemia 1, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cobalamin (Cbl, vitamin B12) transport and metabolism
CD320; CTRC; CTRB1; MMAA; MMADHC; AMN; ELA2; ELA2L; TCN1; LOC100686744
Defective AMN causes hereditary megaloblastic anemia 1
AMN
Defective CUBN causes hereditary megaloblastic anemia 1
AMN
Defects in cobalamin (B12) metabolism
MTRR; MMAA; AMN; MMADHC
Defects in vitamin and cofactor metabolism
MTRR; AMN; MMAA; MMADHC
Disease
CYP11A1; FMOD; FKBP1A; PDCD6IP; CUX1; AP2B1; SUPT5H; CCR5; EPM2A; MIB1
Diseases of metabolism
MMADHC; AMN; GYG2; FDX1L; FDX1; MMAA; EPM2A; CCDC59; MTRR; SFTPC
HDL-mediated lipid transport
BMP1A; APOA1B; Alb; CETP; ABCA1; APOC2; AMN

Protein Function

AMN has several biochemical functions, for example, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMN itself. We selected most functions AMN had, and list some proteins which have the same functions with AMN. You can find most of the proteins on our site.
Function
Related Protein
Function receptor binding
Related Protein TESPA1; SMARCD1; CXADR; CRAT; CD200; LPL; NPFFL; MLN; CNPY4; PTK2AB

AMN Related Articles

Storm, T; Zeitz, C; et al. Detailed investigations of proximal tubular function in Imerslund-Grasbeck syndrome. BMC MEDICAL GENETICS 14:-(2013).
Christensen, EI; Nielsen, R; et al. From bowel to kidneys: the role of cubilin in physiology and disease. NEPHROLOGY DIALYSIS TRANSPLANTATION 28:274-281(2013).