|Official Full Name||ankyrin repeat domain 1 (cardiac muscle)|
|Background||The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.|
|Synonyms||ANKRD1; ankyrin repeat domain 1 (cardiac muscle); ankyrin repeat domain-containing protein 1; ALRP; C 193; CARP; CVARP; MCARP; bA320F15.2; ANKR1_HUMAN; ANKRD 1; Ankyrin repeat domain containing protein 1; C193; Cardiac ankyrin repeat protein; Cytokine inducible nuclear protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; HA1A2; Liver ankyrin repeat domain 1; OTTHUMP00000020084; C-193|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ANKRD1 involved in several pathways and played different roles in them. We selected most pathways ANKRD1 participated on our site, such as Fatty acid, triacylglycerol, and ketone body metabolism, Hypertrophy Model, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANKRD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Fatty acid, triacylglycerol, and ketone body metabolism||ACOT9; ACOT11; SLC25A1; AGPAT2; MED19; MED31; YAP1; ACOT10; AGT; CPT1B|
|Hypertrophy Model||ANKRD1; JUND; CYR61; ADAM10A; HBEGFB; DUSP14; ZEB1B; MSTNB; MYOG; WDR1|
|Metabolism||APOA5; PLIN2; IVD; ABHD4; ACY3.2; CHST9; AGPAT6; GNG13B; GDF1; CYP2U1|
|Metabolism of lipids and lipoproteins||SREBF2; LMF1; CYP24A1; GLIPR1; MED15; CEPT1; CHAT; CYP2N13; APOA4A; SACM1LA|
|PPARA activates gene expression||CDK19; MED6; MED8; MED23; ANKRD1; TIAM2; MED9; MED22; MED20; APOA5|
|Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)||MED19; PLIN2; MED16; MED7; MED29; GLIPR1; MED18; MTF1; MED9; MED15|
ANKRD1 has several biochemical functions, for example, DNA binding, R-SMAD binding, RNA polymerase II transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ANKRD1 itself. We selected most functions ANKRD1 had, and list some proteins which have the same functions with ANKRD1. You can find most of the proteins on our site.
|DNA binding||MEIS4.1A; ZNF829; ZFAND5A; RXRBA; CHD6; ASXL2; ZNF711; ZNF705B; RXRBB; ARNTL|
|R-SMAD binding||SMURF1; SMAD3; MYOCD; ZEB2; SMAD2; TRIM33; AXIN1; SMAD6; PPM1A; JUN|
|RNA polymerase II transcription coactivator activity||MKL1; POU3F1; POU3F2; TBX20; MEF2A; CITED1; CITED4; ISL1; POU1F1; PHF17|
|RNA polymerase II transcription factor binding||NFATC1; MTDH; ZGLP1; GATA5; GATA1A; PITX2; GSK3B; CREBBP; HCLS1; XBP1|
|histone deacetylase binding||PARK2; CBX5; MECP2; HDAC3; MEF2B; DNMT3B; SP1; TAL1; NUDT21; RFXANK|
|p53 binding||HTT; RNF34; TAF1; DUSP26; SMARCA4; SETD7; PSME3; STK11; TP73; RFFL|
|protein binding||TLE3; TOP3B; BMP10; KIAA1524; G6PD; ZBED3; DTX3L; RTDR1; SHC4; SCNN1G|
|titin binding||ANKRD1B; OBSCN; MYBPC3; ANKRD23; ACTN2; CAPN3; TCAP; CAMK2D; ANKRD2; MYBPC1|
|transcription corepressor activity||NR0B2; SMARCA4; HSBP1; TBL1XR1B; ALX1; WNT4; YWHAB; HIF3A; SMYD1; SSX3|
ANKRD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANKRD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANKRD1.
PDE4DIP; DNAJB6; TULP3; DYSF; MYL1; LRPPRC; ARHGDIB; MYOM2; MYBPC1; DST; TTN; REPS1; ASH2L; APPL1