ANXA6 Protein, annexin A6


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Official Full Name annexin A6
Background Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.
Synonyms ANXA6; annexin A6; ANX6; CBP68; 67 kDa calelectrin; Annexin VI; Annexin-6; Calphobindin-II; CPB-II; Chromobindin-20; Lipocortin VI; Protein III; p68; p70; calelectrin; calphobindin II; annexin VI (p68); OTTHUMP00000226119; OTTHUMP00000226120; OTTHUMP00000226122; calcium-binding protein p68e
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ANXA6-001H Recombinant Human ANXA6 Protein, His-tagged E.coli His
    Human ANXA6-1839H Recombinant Human Annexin A6, His-tagged E.coli His
    Human ANXA6-2141H Recombinant Human ANXA6 Protein, GST/His-tagged E.coli GST/His
    Human ANXA6-27320TH Recombinant Human ANXA6, His-tagged E.coli His
    Human ANXA6-27321TH Recombinant Human ANXA6, His-tagged E.coli His
    Human ANXA6-572H Recombinant Human ANXA6 Protein, His-tagged E.coli His
    Human ANXA6-636H Recombinant Human ANXA6 protein, GST-tagged Wheat Germ GST
    Human ANXA6-6862H Recombinant Human ANXA6, His tagged E.coli His
    Human ANXA6-8829HCL Recombinant Human ANXA6 293 Cell Lysate HEK293 N/A
    Human ANXA6-9699H Recombinant Human ANXA, His-tagged E.coli His
    Mouse Anxa6-573M Recombinant Mouse Anxa6 Protein, His-tagged E.coli His
    Chicken ANXA6-6295C Recombinant Chicken ANXA6 Mammalian Cell His
    Zebrafish ANXA6-274Z Recombinant Zebrafish ANXA6 Mammalian Cell His

    ANXA6 involved in several pathways and played different roles in them. We selected most pathways ANXA6 participated on our site, such as Calcium Regulation in the Cardiac Cell, Muscle contraction, Prostaglandin Synthesis and Regulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANXA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcium Regulation in the Cardiac Cell CHRM1; RGS17; CX34.4; GJC1; RGS10; CHRM2; PKIB; CASQ1B; ANXA6; YWHAQ
    Muscle contraction TMEM8C; MYL1; TNNI2; MYLZ3; TRIM72; TNNI2B.2; TMOD3; CMLC1; SMYHC3; ANXA6
    Prostaglandin Synthesis and Regulation ANXA5; ANXA3; CC10; ANXA6; ANXA2; ANXA4; S100A6; S100A10

    ANXA6 has several biochemical functions, for example, GTP binding, calcium ion binding, calcium-dependent phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANXA6 itself. We selected most functions ANXA6 had, and list some proteins which have the same functions with ANXA6. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding SYT5; THBS1; ANXA2; PVALB2; CALR3B; LRP2; CDH12; PPP2R3A; ANXA4; CANT1A
    calcium-dependent phospholipid binding SYT1; SYT7B; RPH3A; SYT5B; RPH3AL; PLA2G4A; ANXA11B; DOC2D; CPNE3; TC2N
    calcium-dependent protein binding SNAP25; TNNC1; SELP; MYO5A; NELF; VPS37B; SYT8; S100A4; KOP; MASP1
    cholesterol binding APOA4A; CETP; TSPO2; APOA2; NPC1; OSBP2; OSBPL3; APOA1A; OSBPL2; TSPO
    ligand-gated ion channel activity GABRB1; P2RX2; TRPA1A; CHRNB2; ANXA6; CHRNA5; CHRNA3; CHRNA4; CHRNB4; CLCA5
    lipid binding ACBD4; ACOT11; OSBPL9; PTGS2; DOK7; MARK2; DNM1L; Fert2; PLTP; PPARD
    protein binding ANKRD24; TMEM115; KLHL3; COX17; RPS27A; RNF146; DNMBP; WHRN; MPG; SH2D4A
    protein homodimerization activity GOLGA5; HM13; NPM1; MTPAP; CRYM; CCDC103; PYCARD; ACCS; ATPIF1; UGT1A3

    ANXA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANXA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANXA6.

    ACTB; ERBB2; MLH1; pilB; ruvB; sucA; CDC73; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; pi3p; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; MME; CD9; GRB2; TJP1; SF1

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