anxa6
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  • Official Full Name
  • annexin A6
  • Background
  • Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.
  • Synonyms
  • ANXA6; annexin A6; ANX6; CBP68; 67 kDa calelectrin; Annexin VI; Annexin-6; Calphobindin-II; CPB-II; Chromobindin-20; Lipocortin VI; Protein III; p68; p70; calelectrin; calphobindin II; annexin VI (p68); OTTHUMP00000226119; OTTHUMP00000226120; OTTHUMP00000226122; calcium-binding protein p68e
Cat.#:ANXA6-2141HTag:GST/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA6 Protein, GST/His-tagged
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Cat.#:ANXA6-572HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA6 Protein, His-tagged
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Cat.#:Anxa6-573MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Anxa6 Protein, His-tagged
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Cat.#:ANXA6-27320THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA6, His-tagged
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Cat.#:ANXA6-27321THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA6, His-tagged
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Cat.#:ANXA6-636HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ANXA6 protein, GST-tagged
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Cat.#:ANXA6-6862HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA6, His tagged
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Cat.#:ANXA6-9699HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA, His-tagged
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Cat.#:ANXA6-6295CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ANXA6
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Cat.#:ANXA6-274ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ANXA6
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Cat.#:ANXA6-1839HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Annexin A6, His-tagged
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Cat.#:ANXA6-8829HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ANXA6 293 Cell Lysate
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Involved Pathway

ANXA6 involved in several pathways and played different roles in them. We selected most pathways ANXA6 participated on our site, such as Calcium Regulation in the Cardiac Cell, Muscle contraction, Prostaglandin Synthesis and Regulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANXA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcium Regulation in the Cardiac Cell
GNB5B; CX34.4; PKIG; RGS10; KCNJ3; RGS20; CX30.3; CHRM3; RGS14; GJC1
Muscle contraction
TNNT3A; MYBPC1; MYL12B; LMOD1; TNNT3; CMLC1; MYBPC3; TMOD1; TNNI1B; TMOD4
Prostaglandin Synthesis and Regulation
S100A10; ANXA5; CC10; S100A6; ANXA3; ANXA6; ANXA4; ANXA2

Protein Function

ANXA6 has several biochemical functions, for example, GTP binding, calcium ion binding, calcium-dependent phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANXA6 itself. We selected most functions ANXA6 had, and list some proteins which have the same functions with ANXA6. You can find most of the proteins on our site.
Function
Related Protein
Function GTP binding
Related Protein TUBA7L; LRRK1; ARF1L; RAB5B; GIMAP8; RAB42; RAB1; SEPT7B; IRGC; RAB25
Function calcium ion binding
Related Protein CAPN3A; HEG; F9B; EFCAB3; CLSTN1; F9; CD248A; PCDHA10; MYL3; CBLB
Function calcium-dependent phospholipid binding
Related Protein ANXA1; SYTL1; ANXA5A; CPNE1; ANXA8; SYT17; ANXA3B; ANXA11; ANXA2B; ANXA1A
Function calcium-dependent protein binding
Related Protein S100PBP; STX2; CHP; CHP1; ANXA3; S100A1; NRXN1; S100P; STMN2; S100A4
Function cholesterol binding
Related Protein ABCG1; ABCA1; STARD6; APOD; APOF; OSBPL10; APOA4A; TSPO; OSBPL1A; PTCH1
Function ligand-gated ion channel activity
Related Protein CHRNB2; CHRNB1; CNGA3; CHRNB4; TRPA1B; CHRNA4; ZACN; CLCA5; CHRNA3; GABRB1
Function lipid binding
Related Protein FABP12; PACSIN3; RASGRP2; SNX10B; GLTP; FNBP1; PLUNC; CRABP2A; APODA.2; APOL6
Function protein binding
Related Protein VMP1; BORA; ZNF124; CBLN3; RBM26; Ar; PPP5C; POLR1C; REXO1L1; FAM19A4
Function protein homodimerization activity
Related Protein ANO2; NPM1; SFTPC; TBX1; TNNC1; BCL2; SMAGP; CARD8; HNF1B; TERFA

Interacting Protein

ANXA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANXA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANXA6.
ACTB; ERBB2; MLH1; pilB; ruvB; sucA; CDC73; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; pi3p; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; MME; CD9; GRB2; TJP1; SF1