|Official Full Name||annexin A6|
|Background||Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.|
|Synonyms||ANXA6; annexin A6; ANX6; CBP68; 67 kDa calelectrin; Annexin VI; Annexin-6; Calphobindin-II; CPB-II; Chromobindin-20; Lipocortin VI; Protein III; p68; p70; calelectrin; calphobindin II; annexin VI (p68); OTTHUMP00000226119; OTTHUMP00000226120; OTTHUMP00000226122; calcium-binding protein p68e|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ANXA6 involved in several pathways and played different roles in them. We selected most pathways ANXA6 participated on our site, such as Calcium Regulation in the Cardiac Cell, Muscle contraction, Prostaglandin Synthesis and Regulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANXA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Calcium Regulation in the Cardiac Cell||CHRM1; RGS17; CX34.4; GJC1; RGS10; CHRM2; PKIB; CASQ1B; ANXA6; YWHAQ|
|Muscle contraction||TMEM8C; MYL1; TNNI2; MYLZ3; TRIM72; TNNI2B.2; TMOD3; CMLC1; SMYHC3; ANXA6|
|Prostaglandin Synthesis and Regulation||ANXA5; ANXA3; CC10; ANXA6; ANXA2; ANXA4; S100A6; S100A10|
ANXA6 has several biochemical functions, for example, GTP binding, calcium ion binding, calcium-dependent phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANXA6 itself. We selected most functions ANXA6 had, and list some proteins which have the same functions with ANXA6. You can find most of the proteins on our site.
|GTP binding||MX2; RHOJ; RTKN; HBS1L; IRGQ2; GTPBP3; SEPT7A; RHOT1A; RHOAD; IRGQ|
|calcium ion binding||SYT5; THBS1; ANXA2; PVALB2; CALR3B; LRP2; CDH12; PPP2R3A; ANXA4; CANT1A|
|calcium-dependent phospholipid binding||SYT1; SYT7B; RPH3A; SYT5B; RPH3AL; PLA2G4A; ANXA11B; DOC2D; CPNE3; TC2N|
|calcium-dependent protein binding||SNAP25; TNNC1; SELP; MYO5A; NELF; VPS37B; SYT8; S100A4; KOP; MASP1|
|cholesterol binding||APOA4A; CETP; TSPO2; APOA2; NPC1; OSBP2; OSBPL3; APOA1A; OSBPL2; TSPO|
|ligand-gated ion channel activity||GABRB1; P2RX2; TRPA1A; CHRNB2; ANXA6; CHRNA5; CHRNA3; CHRNA4; CHRNB4; CLCA5|
|lipid binding||ACBD4; ACOT11; OSBPL9; PTGS2; DOK7; MARK2; DNM1L; Fert2; PLTP; PPARD|
|protein binding||ANKRD24; TMEM115; KLHL3; COX17; RPS27A; RNF146; DNMBP; WHRN; MPG; SH2D4A|
|protein homodimerization activity||GOLGA5; HM13; NPM1; MTPAP; CRYM; CCDC103; PYCARD; ACCS; ATPIF1; UGT1A3|
ANXA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANXA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANXA6.
ACTB; ERBB2; MLH1; pilB; ruvB; sucA; CDC73; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; pi3p; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; MME; CD9; GRB2; TJP1; SF1