Recombinant Human Annexin A6, His-tagged

• Cat.No.: ANXA6-1839H
• Product Overview: Recombinant human Annexin A6 fused to His-tag at N-terminus was expressed inE.coliand purified by using conventional chromatography techniques.MW = 78.0 kDa (693aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Annexin A6 belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin6 has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl.
• Purity: > 90% by SDS – PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHHSSGLVPRGSHMAKPAQGAKYRGSIHDFPGFDPNQDAEALY TAMKG FGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKFERLIVGLM RPPA YCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDLEADIIGDT SGH FQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNRS KQ HLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERL FKAMKGL G TR DNTLIRIMVS RSELDMLDIR EIFRTKYEKS LYSMIKNDTS GEYKKTLLKL SGGDDDAAGQ FFPEAAQVAYQMWELSAVAR VELKGTVRPA NDFNPDADAK ALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISG DLAR LILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKED YHKSL ED ALS SDTSGHFRRI LISLATGHRE EGGENLDQAREDAQVAAEIL EIADTPSGDK TSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIV QSV KNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLH QAIEG DTSGD FLKALLALCG GED.
• Storage: can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: ANXA6 annexin A6 [ Homo sapiens ]
• Synonyms: annexin A6; ANX6; CBP68; ANXA6; p68; p70; CPB-II; annexin-6; calelectrin; lipocortin VI; calphobindin II; calphobindin-II; chromobindin-20; annexin VI (p68); 67 kDa calelectrin; calcium-binding protein p68;Annexin VI; Lipocortin VI; Annexin-6; Protein III; Calphobindin-II; Chromobindin-20
• Gene ID: 309
• mRNA Refseq: NM_001155
• Protein Refseq: NP_001146
• MIM: 114070
• UniProt ID: P08133
• Chromosome Location: 5q32-q34
• Function: calcium ion binding; calcium-dependent phospholipid binding; protein binding