Recombinant Human Annexin A6, His-tagged ANXA6-1839H

Recombinant Human Annexin A6, His-tagged

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Cat.No. : ANXA6-1839H Optional Service: Optional requirements on this protein
Product Overview : Recombinant human Annexin A6 fused to His-tag at N-terminus was expressed inE.coliand purified by using conventional chromatography techniques.MW = 78.0 kDa (693aa).
Description : Annexin A6 belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin6 has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
Source : E.coli.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl.
Purity : > 90% by SDS – PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MAKPAQGAKY RGSIHDFPGF DPNQDAEALY TAMKG FGSDKEAILD IITSRSNRQR QEVCQSYKSL YGKDLIADLK YELTGKFERL IVGLM RPPA YCDAKEIKDA ISGIGTDEKC LIEILASRTN EQMHQLVAAY KDAYERDLEA DIIGDT SGH FQKMLVVLLQ GTREEDDVVS EDLVQQDVQD LYEAGELKWG TDEAQFIYIL GNRS KQ HLRLVFDEYL KTTGKPIEAS IRGELSGDFE KLMLAVVKCI RSTPEYFAER L FKAMKGL G TR DNTLIRIMVS RSELDMLDIR EIFRTKYEKS LYSMIKNDTS GEYKKTLLKL SGGDDDAAGQ FFPEAAQVAYQMWELSAVAR VELKGTVRPA NDFNPDADAK ALRKAMKGLG TDEDTIIDII THRSNVQRQQ IRQTFKSHFG RDLMTDLKSE ISG DLAR LILGLMMPPA HYDAKQLKKA MEGAGTDEKA LIEILATRTN AEIRAINEAY KED YHKSL ED ALS SDTSGHFRRI LISLATGHRE EGGENLDQAREDAQVAAEIL EIADTPSGDK TSLETRFMTI LCTRSYPHLR RVFQEFIKMT NYDVEHTIKK EMSGDVRDAF VAIV QSV KNKPLFFADK LYKSMKGAGT DEKTLTRIMV SRSEIDLLNI RREFIEKYDK SLH QAIEG DTSGD FLKALLALCG GED.
Storage : can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
PDB rendering based on 1avc :

Gene Name : ANXA6 annexin A6 [ Homo sapiens ]
Synonyms : annexin A6; ANX6; CBP68; ANXA6; p68; p70; CPB-II; annexin-6; calelectrin; lipocortin VI; calphobindin II; calphobindin-II; chromobindin-20; annexin VI (p68); 67 kDa calelectrin; calcium-binding protein p68;Annexin VI; Lipocortin VI; Annexin-6; Protein III; Calphobindin-II; Chromobindin-20
Gene ID : 309
mRNA Refseq : NM_001155
Protein Refseq : NP_001146
MIM : 114070
UniProt ID : P08133
Chromosome Location : 5q32-q34
Function : calcium ion binding; calcium-dependent phospholipid binding; protein binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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