AOX1 Protein, aldehyde oxidase 1

AOX1

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AOX1

Official Full Name aldehyde oxidase 1
Background Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis.
Synonyms AOX1; aldehyde oxidase 1; aldehyde oxidase; AO; AOH1
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human AOX1-329H Recombinant Human AOX1 Protein (236-421 aa), His-tagged E.coli His
    Mouse Aox1-617M Recombinant Mouse Aox1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human AOX1-18H Recombinant Human AOX1 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human AOX1-8821HCL Recombinant Human AOX1 293 Cell Lysate HEK293 N/A
    Mouse Aox1-3266M Recombinant Mouse Aox1, His-tagged E.Coli or Yeast His
    Rat AOX1-694R Recombinant Rat AOX1 Protein Mammalian Cell His
    Cynomolgus Monkey AOX1-300C Recombinant Cynomolgus AOX1 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque AOX1-341R Recombinant Rhesus monkey AOX1 Protein, His-tagged Mammalian Cell His
    Chicken AOX1-3316C Recombinant Chicken AOX1 Mammalian Cell His
    Zebrafish AOX1-8315Z Recombinant Zebrafish AOX1 Mammalian Cell His

    AOX1 involved in several pathways and played different roles in them. We selected most pathways AOX1 participated on our site, such as Valine, leucine and isoleucine degradation, Tyrosine metabolism, Tryptophan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AOX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Valine, leucine and isoleucine degradation ALDH6A1; ALDH9A1B; ACAT1; HSD17B10; ACAA2; HMGCS2; HADHA; AUH; ALDH2.2; AOX3L1
    Tyrosine metabolism HPD; DBH; TH; TAT; GOT1; AOX3; IL4I1; ADH2-2; ADH1; COMTB
    Tryptophan metabolism TDO2; CCBL2; GCDHB; OGDHA; ANI_1_2390104; AOX3L1; ALDH2.2; OGDHL; ALDH1B1; TPH1
    Vitamin B metabolism AOX3; AOX2P; PSAT1; PNPO; PDXKA; PDXK; PDXKB; AOX1; PDXP; AOX3L1
    Nicotinate and nicotinamide metabolism NAPRT1; QPRT; KCNG4; AOX3; NMNAT1; NUDT12; NT5C1B; NADKA; NADSYN1; NT5M
    Retinol metabolism ADH1; UGT1A6; SDR16C5B; UGT5G1; HSD17B6; DHRS3B; UGT1A1; ALDH1A1; CYP26B1; Aldh1a7
    Drug metabolism - cytochrome P GSTM3; AOX1; MGST1; UGT5G1; GSTA; FMO6P; AOX3; ALDH3B1; GSTM5; MGST3
    Metabolic pathways B4GALT4; GK2; AGXT; CDO1; ALDH1A3; ALG2; PRIM2; PTGES3A; NDUFS8; GATC
    Jak-STAT signaling pathway IL28RA; PIK3R3; GH2; IL11RA2; MTOR; CCND3; IL15; STAT5B; CNTFR; IL3

    AOX1 has several biochemical functions, for example, 2 iron, 2 sulfur cluster binding, NAD binding, aldehyde oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AOX1 itself. We selected most functions AOX1 had, and list some proteins which have the same functions with AOX1. You can find most of the proteins on our site.

    Function Related Protein
    2 iron, 2 sulfur cluster binding RFESD; XDH; FDX1B; AOX3L1; CMAH; NDUFS1; ISCUB; SDHB; FDX1; GLRX2
    NAD binding IDH2; IDH3B; UGDH; AOX4; ADH4; NDUFV1; GPD1L; NNT; HADHA; HSD3B5
    aldehyde oxidase activity AOX1; AOX3; AOX4; AOX3L1; ADH7
    electron carrier activity AOX1; AOC2; ETFDH; CIAPIN1; CYP1A2; QDPR; HAAO; ACOX3; IDH3B; AOX4
    flavin adenine dinucleotide binding NOX5; NDOR1; TXNRD2; MAOB; TXNRD3; SQLEA; ACADM; CHDH; AIFM3; NOX4
    iron ion binding FTH1; HBB; CYP2AA1; CYP27A1; CYP3A7; LEPREL1; CYP2C39; CYP3A5; C14orf169; CYP1C1
    molybdopterin cofactor binding SUOX; XDH; MARC2; MARC1; AOX1; MOSC2
    oxidoreductase activity, acting on CH-OH group of donors AOX1; GULO; AGPS; XDH; DHCR24; AOX3; AOX4; AOX3L1
    xanthine dehydrogenase activity XDH; AOX1

    AOX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AOX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AOX1.

    RBL1; GK; CRKL; RCHY1

    Kim, S; Warburton, S; et al. Regulation of alcohol oxidase 1 (AOX1) promoter and peroxisome biogenesis in different fermentation processes in Pichia pastoris. JOURNAL OF BIOTECHNOLOGY 166:174-181(2013).
    Tu, YB; Wang, YQ; et al. High-level expression and immunogenicity of a porcine circovirus type 2 capsid protein through codon optimization in Pichia pastoris. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 97:2867-2875(2013).

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