ap4m1
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  • Official Full Name
  • adaptor-related protein complex 4, mu 1 subunit
  • Background
  • This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system.
  • Synonyms
  • AP4M1; adaptor-related protein complex 4, mu 1 subunit; AP-4 complex subunit mu-1; adaptor related protein complex AP 4 mu4 subunit; AP 4 adapter complex mu subunit; mu subunit of AP 4; MU 4; mu adaptin related protein 2; MU ARP2; Adaptor related protein complex 4 mu 1 subunit; Adaptor related protein complex AP4 mu4 subunit; Adaptor-related protein complex AP-4, mu 1; AP 4 complex subunit mu 1; AP4 adapter complex mu subunit; AP4 complex subunit mu 1; Ap4m4; CPSQ3; MU4; Mu4-adaptin; MUARP 2; MUARP2; OTTHUMP00000206506; OTTHUMP00000206588; OTTHUMP00000206591; OTTHUMP00000206630; OTTHUMP00000206943; OTTHUMP00000206944; mu subunit of AP-4; mu-adaptin-related protein 2; mu-adaptin-related protein-2; adapter-related protei; MU-4; MU-ARP2
Cat.#:AP4M1-3544HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human AP4M1, His-tagged
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Cat.#:AP4M1-663HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human AP4M1 protein, GST-tagged
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Cat.#:AP4M1-1752MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse AP4M1 Protein
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Cat.#:AP4M1-704RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat AP4M1 Protein
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Cat.#:AP4M1-6698CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken AP4M1
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Cat.#:AP4M1-779ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish AP4M1
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Cat.#:AP4M1-88HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human AP4M1 cell lysate
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Involved Pathway

AP4M1 involved in several pathways and played different roles in them. We selected most pathways AP4M1 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP4M1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Lysosome
FUCA1; CTSH; NAPSA; AP3S2; ATP6V0A2B; TPP1; CLTCA; SLC11A2; ATP6V0A1A; CTSK

Protein Function

AP4M1 has several biochemical functions, for example, protein binding, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AP4M1 itself. We selected most functions AP4M1 had, and list some proteins which have the same functions with AP4M1. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein BCL7A; PKP1; CDC42EP5; AGXT2L2; DNALI1; TMIGD2; PSAP; KRTAP10-11; RERE; RALGDS
Function transporter activity
Related Protein CRABP2A; NUTF2; ABCC6; SLC2A3A; NUP98; AP2S1; CDH17; SLC5A3A; SYP; SLC4A4A

Interacting Protein

AP4M1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP4M1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP4M1.
USP47; tax; ZBTB22; CHTF8; DDX52; b4dnw0_human; SF3B2; H3F3B; CBX4; LCMT2; RALA; IMPDH2; HMGA1; CDK11B; AKT2; GALNT2; NPAT

AP4M1 Related Articles

Abdollahpour, H; Alawi, M; et al. An AP4B1 frameshift mutation in siblings with intellectual disability and spastic tetraplegia further delineates the AP-4 deficiency syndrome. EUROPEAN JOURNAL OF HUMAN GENETICS 23:256-259(2015).
Jameel, M; Klar, J; et al. A novel AP4M1 mutation in autosomal recessive cerebral palsy syndrome and clinical expansion of AP-4 deficiency. BMC MEDICAL GENETICS 15:-(2014).