arpc3
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  • Official Full Name
  • actin related protein 2/3 complex, subunit 3, 21kDa
  • Background
  • This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p21 subunit, has yet to be determined.
  • Synonyms
  • ARPC3; actin related protein 2/3 complex, subunit 3, 21kDa; actin related protein 2/3 complex, subunit 3 (21 kD); actin-related protein 2/3 complex subunit 3; ARC21; p21 Arc; Actin related protein 2/3 complex subunit 3; ARP2/3 complex 21 kDa subunit; ARP2/3 protein complex subunit p21; p21-Arc
Cat.#:ARPC3-2793HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ARPC3 Protein, MYC/DDK-tagged
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Cat.#:ARPC3-7591HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ARPC3, His-tagged
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Cat.#:ARPC3-847HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ARPC3 protein, GST-tagged
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Cat.#:ARPC3-9884HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ARPC3, GST-tagged
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Cat.#:ARPC3-1968MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ARPC3 Protein
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Cat.#:ARPC3-417RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ARPC3 Protein, His-tagged
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Cat.#:ARPC3-4880CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ARPC3
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Cat.#:ARPC3-342ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ARPC3
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Cat.#:ARPC3-37HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human ARPC3 lysate
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Involved Pathway

ARPC3 involved in several pathways and played different roles in them. We selected most pathways ARPC3 participated on our site, such as Axon guidance, B Cell Receptor Signaling Pathway, Bacterial invasion of epithelial cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARPC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Axon guidance
GPC1B; LAMTOR2; KALRNB; SEMA3E; TRPC4; AP2A1; NADL1.1; ITGB3A; SCN3B; Ntng2
B Cell Receptor Signaling Pathway
IGHM; PIK3CG; Cd79a, Cd79b; CD79A; CD79B; PILRB; PIK3AP1; NFATC1; BTK; CD22
Bacterial invasion of epithelial cells
PIK3R5; CTNNA1; CLTC; CAV2; PIK3R2; PIK3CA; SEPT12; CRKL; CLTA; ILK
CDC42 signaling events
TNK2; PAK4; BAIAP2; EPS8; ARPC4; ARPC3; CFL1; CDC42BPA; ARPC1B; CTNNA1
Developmental Biology
EPHA10; HFE2; CFC1; COL4A4; PEA15; NR6A1; MED6; COL6A1; DUSP2; CLTA
EPH-Ephrin signaling
ARPC2; EFNA4; ARPC5; EFNA3B; KDR; EFNB2A; EFNA1B; EFNB3; DNM1; AP2A2
EPHB-mediated forward signaling
CFL1; ARPC1B; EFNB3B; EPHB4B; ARPC3; ACTR2; KALRN; ACTR3; ITSN1; KALRNB
Endocytosis
DNM2A; MVB12BA; NEDD4; KITA; DNM1B; RAB5AA; VPS37B; BF2; PRKCZ; CXCR4

Protein Function

ARPC3 has several biochemical functions, for example, contributes_to actin filament binding, protein binding, structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by ARPC3 itself. We selected most functions ARPC3 had, and list some proteins which have the same functions with ARPC3. You can find most of the proteins on our site.
Function
Related Protein
Function contributes_to actin filament binding
Related Protein ARPC2; ARPC4; ACTR2; ARPC3; ACTR3; MYH9; MYH10; ARPC1B; ARPC5
Function protein binding
Related Protein TSN; PEX11G; HELZ; AMBP; KIF18A; RCN3; HES1; N6AMT1; CNKSR3; KPNB1
Function structural constituent of cytoskeleton
Related Protein ARPC4; GFAP; TLN1; SPRR2A1; TUBA8L2; NDC80; TUBA1L2; TUBGCP4; ACTB; TUBA8

Interacting Protein

ARPC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARPC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARPC3.
WASL; HOXA3; NRIP1; GOLGA2; VCAM1; Ptms; ACTR3B; LTA4H; CETP

ARPC3 Related Articles

Schmidt, S; Willers, J; et al. Effect of omega-3 polyunsaturated fatty acids on the cytoskeleton: an open-label intervention study. LIPIDS IN HEALTH AND DISEASE 14:-(2015).
Yang, WL; Thein, S; et al. Arp2/3 complex regulates adipogenesis by controlling cortical actin remodelling. BIOCHEMICAL JOURNAL 464:179-192(2014).