ARSJ
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Official Full Name
arylsulfatase family, member J
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Synonyms
ARSJ;arylsulfatase family, member J;26286;ENSG00000180801;4q26;FLJ23548;arylsulfatase J;arylsulfatase J;ASJ;EC 3.1.6.12;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ARSJ-867H | Recombinant Human ARSJ protein, GST-tagged | Wheat Germ | GST |
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| Human | ARSJ-8674HCL | Recombinant Human ARSJ 293 Cell Lysate | HEK293 | N/A |
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| Human | ARSJ-1302HF | Recombinant Full Length Human ARSJ Protein, GST-tagged | In Vitro Cell Free System | GST | 85 amino acids |
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- Involved Pathway
- Protein Function
- Interacting Protein
ARSJ involved in several pathways and played different roles in them. We selected most pathways ARSJ participated on our site, such as Gamma carboxylation, hypusine formation and arylsulfatase activation, Glycosphingolipid metabolism, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARSJ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Gamma carboxylation, hypusine formation and arylsulfatase activation | DPH5;SUMF2;OTOP2;EIF5A2;EIF5A;ARSH;F9A;DPH3;ARSE |
| Glycosphingolipid metabolism | ARSI;ARSD;GLTPD1;ARSE;ARSJ;GLTP;SUMF2;NEU4;ARSK |
| Metabolism | ABHD4;KIAA1199;PPM1LA;DGUOK;FA2H;SLC6A8;BCHE;CYP51A1;CPNE1 |
| Metabolism of lipids and lipoproteins | ACSF2;AGPAT6;SLC27A2;MED19;DHCR24;DPEP1;SGMS2;SLC27A5;CDK19 |
| Metabolism of proteins | SLC30A6;GALNT6;IGFBP4;CPB1;RAB27A;HSCB;SEC63;TIMM9;GPR119 |
| Post-translational protein modification | ARSH;DPH5;MAN1B1;ARSI;SLC35A1;GNE;MUC5AC;GALNTL5;MPDU1A |
| Sphingolipid metabolism | PPAP2C;UGT8A;CERS3B;CERS1;LASS1;SMPD5;GAL3ST1;B4GALT6;ACER3 |
| The activation of arylsulfatases | ARSI;SUMF2;ARSH;ARSF;ARSK;ARSJ |
ARSJ has several biochemical functions, for example, arylsulfatase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARSJ itself. We selected most functions ARSJ had, and list some proteins which have the same functions with ARSJ. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| arylsulfatase activity | SULF1;ARSE;ARSA;SULF2;ARSF;ARSD;ARSB;ARSK;ARSG |
| metal ion binding | NMRK2;TRMT1L;MTL5;ATP1A1A.5;ZFP704;BMP1A;KITA;PRKCDA;ZYMND12 |
ARSJ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARSJ here. Most of them are supplied by our site. Hope this information will be useful for your research of ARSJ.
- Q&As
- Reviews
Q&As (7)
Ask a questionCurrently, there is limited information on animal models specifically targeting the ARSJ protein. However, studies using various animal models have provided insights into the molecular processes and associated diseases affected by altered ARSJ function.
The ARSJ protein is typically found in the lysosomes, which are membrane-bound compartments within cells responsible for breaking down various molecules.
Yes, the ARSJ protein is conserved among different species, indicating its importance in sulfate metabolism throughout evolution.
Currently, there are no specific therapies targeting the ARSJ protein. However, further research may identify potential therapeutic approaches that could modulate ARSJ function in diseases associated with sulfate metabolism disturbances.
Yes, the ARSJ protein has been shown to interact with other proteins involved in sulfate metabolism, such as ARSI (arylsulfatase I) and ARSK (arylsulfatase K). These interactions likely play a role in coordinating sulfate removal in various tissues.
The regulatory mechanisms controlling ARSJ protein expression and activity are not fully understood. However, research suggests that transcriptional regulation and post-translational modifications may influence its expression and enzymatic activity.
Mutations in the ARSJ gene have been linked to a rare genetic disorder called X-linked chondrodysplasia punctata 1 (CDPX1), which is characterized by skeletal abnormalities and developmental defects.
Customer Reviews (3)
Write a reviewI highly recommend the ARSJ protein for various experimental applications.
It has demonstrated outstanding performance in ELISA, providing reliable and precise results.
I am certain that the ARSJ protein will play a pivotal role in facilitating robust and insightful research, providing the assurance of reliable and consistent results.
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