b3gnt2
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  • Official Full Name
  • UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
  • Background
  • This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains.
  • Synonyms
  • B3GNT2; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2; B3GNT1, UDP GlcNAc:betaGal beta 1,3 N acetylglucosaminyltransferase 1; B3GN T1; B3GN T2; B3GNT 2; BETA3GNT; B3GNT; Beta 1 3 galactosyltransferase 7; Beta3Gn T1; beta3Gn-T1; beta3Gn-T2; beta-1,3-Gn-T1; beta-1,3-Gn-T2; beta-1,3-N-acetylglucosaminyltransferase bGnT-1; beta-1,3-N-acetylglucosaminyltransferase bGnT-2; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1; BGNT2; B3GNT1; BGnT-2; B3GN-T2; B3GNT-2
Cat.#:B3GNT2-2216HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human B3GNT2 Protein, MYC/DDK-tagged
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Cat.#:B3GNT2-930HTag:His
Source (Host):NS0Species:Human
Product nameRecombinant Human B3GNT2 Protein, His-tagged
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Cat.#:B3GNT2-018HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human B3GNT2 protein, GST-tagged
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Cat.#:B3GNT2-019HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human B3GNT2 protein, GST-tagged
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Cat.#:B3GNT2-10103HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human B3GNT2, His-tagged
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Cat.#:B3GNT2-8546HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human B3GNT2, Fc tagged
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Cat.#:B3GNT2-494RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey B3GNT2 Protein, His-tagged
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Cat.#:B3GNT2-1835CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken B3GNT2
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Cat.#:B3GNT2-1396HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human B3GNT2 cell lysate
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Involved Pathway

B3GNT2 involved in several pathways and played different roles in them. We selected most pathways B3GNT2 participated on our site, such as Glycosaminoglycan biosynthesis - keratan sulfate, Glycosaminoglycan metabolism, Glycosphingolipid biosynthesis - lacto and neolacto series, which may be useful for your reference. Also, other proteins which involved in the same pathway with B3GNT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycosaminoglycan biosynthesis - keratan sulfate
B4GALT3; B3GNT2B; CHST6; Chst5; CHST1; CHST4; B3GNT7; FUT8; ST3GAL3B; B4GALT2
Glycosaminoglycan metabolism
SLC35B2; CHST14; GLB1L; DSEL; GPC1A; OMD; B3GNT2A; SLC26A2; LYVE1; FMODA
Glycosphingolipid biosynthesis - lacto and neolacto series
B3GNT4; ST3GAL4; FUT1; B3GALT2; B4GALT3; ST8SIA1; FUT9; B3GNT1; FUT7; B4GALT4
Keratan sulfate biosynthesis
OMD; FMODA; ST3GAL3A; OGN; SLC35D2; KERA; B3GNT2; B3GNT2A; B3GNT1; B3GNT3
Keratan sulfate/keratin metabolism
SLC35D2; B3GNT2A; FMODA; GLB1L; B3GNT3; OMD; ST3GAL3A; B3GNT1; B3GNT2
Metabolic pathways
COX4I1; TGDS; NDUFA9; DEGS1; CKB; LCT; POLR2J3; OGDHA; MGAT5B; DEGS2
Metabolism
ADH8A; BRP44; SULT1C2; LYRM4; SLC25A32A; ACY3.1; CYP51A1; B3GNT1; ALOX5AP; ARSH
Metabolism of carbohydrates
PFKLB; AGL; SLC25A10; SLC26A2; SLC5A9; SLC26A1; DSEL; EPM2A; HS3ST4; LYVE1

Protein Function

B3GNT2 has several biochemical functions, for example, N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity, galactosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by B3GNT2 itself. We selected most functions B3GNT2 had, and list some proteins which have the same functions with B3GNT2. You can find most of the proteins on our site.
Function
Related Protein
Function N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity
Related Protein B3GNT3; B3GNT4; B3GNT1; GCNT2; B3GNT2
Function galactosyltransferase activity
Related Protein B3GNT9-PS; B3GNT4; B3GNT7; B3GNT6; GALNT18A; PIGB; B4GALT7; B3GNT5; B3GNT3; B3GALNT2

Interacting Protein

B3GNT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with B3GNT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of B3GNT2.
TMEM246