bmp5
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  • Official Full Name
  • bone morphogenetic protein 5
  • Background
  • This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors.
  • Synonyms
  • BMP5; bone morphogenetic protein 5; BMP-5; MGC34244
Cat.#:BMP5-259HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BMP5 Protein, His-tagged
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Cat.#:Bmp5-260MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Bmp5 Protein, His-tagged
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Cat.#:BMP5-05HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human BMP5, Fc tagged
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Cat.#:BMP5-268HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BMP5 Protein, GST-tagged
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Cat.#:BMP5-269HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BMP5 Protein, GST-tagged
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Cat.#:BMP5-270HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BMP5 Protein, GST-tagged
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Cat.#:BMP5-271HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BMP5 Protein, GST-tagged
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Cat.#:BMP5-272HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BMP5 Protein, GST-tagged
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Cat.#:BMP5-8317HTag:
Source (Host):NS0Species:Human
Product nameRecombinant Human BMP5
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Cat.#:BMP5-6705CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken BMP5
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Cat.#:BMP5-11279ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish BMP5
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Cat.#:BMP5-26HTag:
Source (Host):NS0Species:Human
Product nameRecombinant Human Bone Morphogenetic Protein 5
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Cat.#:BMP5-27HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Bone Morphogenetic Protein 5
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Cat.#:BMP5-11HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Bone Morphogenetic Protein 5
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Cat.#:BMP5-3074HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human BMP5 cell lysate
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Involved Pathway

BMP5 involved in several pathways and played different roles in them. We selected most pathways BMP5 participated on our site, such as TGF-beta signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMP5 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
TGF-beta signaling pathway
ID2A; TGIF1; SP1; ZFYVE16; BMPR2B; LEFTY1; NOG; INHBA; RBX1; TGFB1A
Hippo signaling pathway
WNT10B; MOB1A; FGF1; PPP1CC; ID2; WNT7A; FZD2; FZD1; SOX2; TGFBR1

Protein Function

BMP5 has several biochemical functions, for example, BMP receptor binding, cytokine activity, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BMP5 itself. We selected most functions BMP5 had, and list some proteins which have the same functions with BMP5. You can find most of the proteins on our site.
Function
Related Protein
Function BMP receptor binding
Related Protein BMP6; BMP8B; BMP5; BMP3; BMP7B; PYCARD; BMP7A; BMP2; BMP4; BMP7
Function cytokine activity
Related Protein CMTM2B; IFNE; IL15L; GM13278; FASLG; IFN-a; OSTN; IL28A; GDF2; Gm13290
Function growth factor activity
Related Protein FGF14; OSGIN1; NRG4; REG1A; BMP4; ENDOU; CLEC11A; GDF11; IL5; CLCF1
Function transforming growth factor beta receptor binding
Related Protein LFT1; GDF3; BMP3; INHBAA; BMP10; LRG1; FKBP1A; BMP8A; NDR2; USP15

BMP5 Related Articles

Endo, Y; Ishiwata-Endo, H; et al. Cloning and characterization of chicken alpha 5 integrin: Endogenous and experimental expression in early chicken embryos. MATRIX BIOLOGY 32:381-386(2013).
Guan, QN; Li, SY; et al. Reduction of chronic rejection of renal allografts by anti-transforming growth factor-beta antibody therapy in a rat model. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 305:F199-F207(2013).

BMP5 Related Gene Family

TGF