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BRD2

  • Official Full Name

    bromodomain containing 2

  • Overview

    Brd2 is a highly conserved member of the BET subfamily of bromodomain proteins that contain two tandem N-terminal bromodomains and a single C-terminal extra-terminal (ET) domain (1). In addition to its involvement in guiding the expression of cell cycle g
  • Synonyms

    BRD2; bromodomain containing 2; bromodomain-containing protein 2; D6S113E; FSRG1; KIAA9001; NAT; RING3; O27.1.1; bromodomain-containing 2; really interesting new gene 3 protein; female sterile homeotic-related gene 1; FSH; RNF3; FLJ31942; DKFZp686N0336;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Chicken
  • Human
  • Rat
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|Flag
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BRD2-35H Active Recombinant Human BRD2, His&FLAG-tagged E.coli His/Flag
Human BRD2-27674TH Recombinant Human BRD2 Wheat Germ N/A 90 amino acids
Human BRD2-653H Recombinant Human bromodomain containing 2, His-tagged E.coli His
Human BRD2-90H Recombinant Human BRD2 protein, GST-tagged E.coli GST 2-473
Human BRD2-329H Recombinant Human BRD2 Protein, GST-tagged Wheat Germ GST
Human BRD2-91H Recombinant Human BRD2 protein, His-tagged E.coli His 2-473
Human BRD2-177HCL Recombinant Human BRD2 cell lysate N/A
Human BRD2-34H Active Recombinant Human BRD2 Protein (339-459), N-His tagged E.coli N-His 339-459
Human BRD2-01H Recombinant Human BRD2 Protein, His-tagged E.coli His
Human BRD2-3784HF Recombinant Full Length Human BRD2 Protein, GST-tagged In Vitro Cell Free System GST 801 amino acids
Rat BRD2-1012R Recombinant Rat BRD2 Protein Mammalian Cell His
Rat BRD2-670R-B Recombinant Rat BRD2 Protein Pre-coupled Magnetic Beads HEK293
Rat BRD2-670R Recombinant Rat BRD2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken BRD2-2378C Recombinant Chicken BRD2 Mammalian Cell His
Kit-1925 BRD2 bromodomain 2 TR-FRET Assay Kit N/A
Kit-1924 BRD2 bromodomain 1 TR-FRET Assay Kit N/A
Kit-1640 HEK 293 BRD2(1) Bromodomain Assay Kit N/A
Kit-1691 BRD2 (BD1+BD2) TR-FRET Assay Kit N/A
Kit-1926 BRD2 bromodomains 1 and 2 TR-FRET Assay Kit N/A
Kit-1692 BRD2 (BD2) Inhibitor Screening Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

BRD2 involved in several pathways and played different roles in them. We selected most pathways BRD2 participated on our site, such as Regulation of retinoblastoma protein, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Regulation of retinoblastoma proteinMYOD1;SMARCB1;BGLAP;ATF7;CBX4;BRD2;CKM;AATF;ELF1

BRD2 has several biochemical functions, for example, chromatin binding, lysine-acetylated histone binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRD2 itself. We selected most functions BRD2 had, and list some proteins which have the same functions with BRD2. You can find most of the proteins on our site.

Function Related Protein
chromatin bindingCAPNS2;MCM5;HMG20A;FOXN4;CIC;TLE4;IFT74;SIRT7;POLE
lysine-acetylated histone bindingTRIM24;PSME4;BRD4;BRD2;PSME4B;BRDT;SMARCA4;ATAD2B;TAF1
protein bindingMPZL2;DOCK9;CWC15;Cd24a;EIF2B5;ADRM1;MFF;RSL24D1;ABCF1

BRD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BRD2.

RUNX3; HIST2H4B; CSNK2A2; mutT7; POLR2B; CSNK2A1; myc_human_gene; IL7R

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