brf2
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  • Official Full Name
  • BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like
  • Background
  • This gene encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product of this gene, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with the TATA-binding protein.
  • Synonyms
  • BRF2; BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like; transcription factor IIIB 50 kDa subunit; BRFU; FLJ11052; TFIIIB50; B-related factor 2; BRF-2; BRF2_HUMAN; hBRFU; hTFIIIB50; RNA polymerase III transcription initiation factor BRF2; Transcription factor IIB- related factor TFIIIB50; transcription factor IIB- related factor, TFIIIB50; RNA polymerase III transcription initiation factor BRFU
Cat.#:BRF2-10288HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BRF2, GST-tagged
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Cat.#:BRF2-337HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BRF2 Protein, GST-tagged
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Cat.#:BRF2-2491MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse BRF2 Protein
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Cat.#:BRF2-1014RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat BRF2 Protein
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Cat.#:BRF2-350CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus BRF2 Protein, His-tagged
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Cat.#:BRF2-972ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish BRF2
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Cat.#:BRF2-8408HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human BRF2 293 Cell Lysate
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Involved Pathway

BRF2 involved in several pathways and played different roles in them. We selected most pathways BRF2 participated on our site, such as Gene Expression, RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, RNA Polymerase III Abortive And Retractive Initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRF2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Gene Expression
PCBP2; ZNF285A; ZKSCAN1; SUZ12B; METTL14; ZNF334; ZNF79; UBTF; COBRA1; SEC61B
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
POLR3GLA; POU2F1; PTRF; POLRMT; ZFP143; SNAPC2; SNAPC1; NFIC; GTF3C5; GTF3AB
RNA Polymerase III Abortive And Retractive Initiation
SNAPC4; BRF2; CRCP; SNAPC5; ZNF143; GTF3C5; GTF3C4; BRF1; NFIC; SNAPC1
RNA Polymerase III Transcription
POLR3GLA; NFIC; GTF3C4; SNAPC4; NFIA; BRF2; NFIB; SNAPC5; ZNF143; GTF3C2
RNA Polymerase III Transcription Initiation
SNAPC1B; SNAPC4; GTF3C3; SNAPC1A; SNAPC2; GTF3AB; ZNF143; ZFP143; BRF1; GTF3C4
RNA Polymerase III Transcription Initiation From Type 3 Promoter
ZNF143; SNAPC4; SNAPC1B; BRF2; ZNF143B; POU2F1B; SNAPC5; SNAPC1A; SNAPC1; SNAPC3

Protein Function

BRF2 has several biochemical functions, for example, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRF2 itself. We selected most functions BRF2 had, and list some proteins which have the same functions with BRF2. You can find most of the proteins on our site.
Function
Related Protein
Function zinc ion binding
Related Protein BLVRA; HNF4A; NR5A1; RNF13; RNF133; CHD4A; KAT6B; DTNB; ZZEF1; SEC24C

Interacting Protein

BRF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BRF2.
TIMM23; SURF4; PSMD3; ZW10; MYO1B; DPM1; SF3B1; AIFM1; HSPB1; SLC3A2; PDHB; TBP; KDELR1; ABCD3; MCM7; COPB2; ARL1

BRF2 Related Articles

Reznik, B; Clement, SL; et al. hnRNP F Complexes with Tristetraprolin and Stimulates ARE-mRNA Decay. PLOS ONE 9:-(2014).
Adolph, C; Akhunzyanov, R; et al. Measurement of radiative widths of a(2)(1320) and pi(2)(1670). EUROPEAN PHYSICAL JOURNAL A 50:-(2014).