|Official Full Name||core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1|
|Background||The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.|
|Synonyms||C1GALT1; core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; C1GALT; core 1 beta3 Gal T; T synthase; B3Gal-T8; core 1 beta3-Gal-T1; core 1 O-glycan T-synth|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
C1GALT1 involved in several pathways and played different roles in them. We selected most pathways C1GALT1 participated on our site, such as Mucin type O-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with C1GALT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Mucin type O-Glycan biosynthesis||C1GALT1; C1GALT1B; GALNTL6; GALNT11; GALNTL5; GALNT2; ST3GAL2; GALNT4; GCNT1; POC1BL|
|Metabolic pathways||PDHB; DPYD; HSD17B7; GCDHB; GALNT7; CKM; NME3; SEPHS1; PAFAH1B1B; DLAT|
C1GALT1 has several biochemical functions, for example, galactosyltransferase activity, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C1GALT1 itself. We selected most functions C1GALT1 had, and list some proteins which have the same functions with C1GALT1. You can find most of the proteins on our site.
|galactosyltransferase activity||B3GNT8; B3GNT3; C1GALT1; B3GNTL1; GTDC2; A4GALT; B4GALT4; B3GNT5A; B3GALNT2; B4GALT5|
|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity||C1GALT1A; C1GALT1C1; C1GALT1B; C1GALT1|
|metal ion binding||GFI1AA; SDHC; ALKBH4; GNAL; PDE8A; SP8A; ADAL; LNX2B; RORAA; NUDT14|
|transferase activity||WNK2; SPS2; XYLT1; TRIO; SULT3ST2; ACAA1A; MBOAT1; SBK3; KEG1; UGT1A7C|
|transferase activity, transferring glycosyl groups||ST3GAL3A; UGT1A2; UGT1B4; UGT5G1; UGT1AB; GYG1B; UGT5C1; UGT2A4; MGAT3A; UGT5A4|
C1GALT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C1GALT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of C1GALT1.