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CARD10

Official Full Name

caspase recruitment domain family, member 10
Overview

The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001
Synonyms

CARD10; caspase recruitment domain family, member 10; caspase recruitment domain-containing protein 10; BIMP1; CARMA3; carma 3; CARD-containing MAGUK 3 protein; CARD-containing MAGUK protein 3; Bcl10 binding protein and activator of NFKB; MGC142219;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	CARD10-0390H	Recombinant Human CARD10 Protein, GST-Tagged	Wheat Germ	GST	Inquiry
Human	CARD10-7851HCL	Recombinant Human CARD10 293 Cell Lysate	HEK293	N/A	Inquiry
Mouse	Card10-286M	Recombinant Mouse Card10 Protein, MYC/DDK-tagged	HEK293T	MYC/DDK	Inquiry

Involved Pathway
Protein Function
Interacting Protein

CARD10 involved in several pathways and played different roles in them. We selected most pathways CARD10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CARD10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

CARD10 has several biochemical functions, for example, protein binding, receptor signaling complex scaffold activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CARD10 itself. We selected most functions CARD10 had, and list some proteins which have the same functions with CARD10. You can find most of the proteins on our site.

Function	Related Protein
protein binding	DROSHA;DOK2;RSL24D1;ZFP110;PALB2;SLC1A5;C16orf79;JUN;GLRB
receptor signaling complex scaffold activity	LDLRAP1;MAGI2;MAPK8IP3;DEDD2;CD3E;GRIP1;CARD10;NUP62;NCK1

CARD10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CARD10 here. Most of them are supplied by our site. Hope this information will be useful for your research of CARD10.

ATXN7; Kif7; MYO1C; KIF20A; CAPZA2; Kif20a; DBN1; Myh10; MYO19; CDC5L; Myo1c