cbx1
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  • Official Full Name
  • CBX1 chromobox homolog 1
  • Background
  • This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The;protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal;chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain;(CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone;proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression.;Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding;the same protein, have been identified.
  • Synonyms
  • CBX1; chromobox homolog 1; chromobox homolog 1 (Drosophila HP1 beta); chromobox protein homolog 1; CBX; HP1 beta homolog (Drosophila ); HP1 BETA; HP1Hs beta; M31; MOD1; HP1 beta homolog; modifier 1 protein; heterochromatin protein 1-beta; heterochromatin protein p25 beta; heterochromatin protein 1 homolog beta; chromobox homolog 1 (HP1 beta homolog Drosophila ); p25beta; HP1-BETA; HP1Hsbeta; HP1Hs-beta;
Cat.#:CBX1-0477HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CBX1 Protein, GST-Tagged
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Cat.#:CBX1-2721HTag:DDK
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human CBX1 Protein, DDK-tagged
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Cat.#:CBX1-3580HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CBX1, His-tagged
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Cat.#:CBX1-105HTag:Strep
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human CBX1 Protein, Strep-tagged
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Cat.#:CBX1-10766HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CBX1, GST-tagged
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Cat.#:CBX1-253HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CBX1 protein, GST-tagged
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Cat.#:CBX1-364CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CBX1 Protein, His-tagged
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Cat.#:CBX1-5904CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CBX1
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Cat.#:CBX1-7807HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CBX1 293 Cell Lysate
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Protein Function

CBX1 has several biochemical functions, for example, chromatin binding, enzyme binding, histone methyltransferase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CBX1 itself. We selected most functions CBX1 had, and list some proteins which have the same functions with CBX1. You can find most of the proteins on our site.
Function
Related Protein
Function chromatin binding
Related Protein PELP1; NSBP1; REL; TRIM24; HMGB3; RNF20; GATA6; PRKCBB; EP300; FANCM
Function enzyme binding
Related Protein TTN; NOP14; PHB; HDAC10; UBE2I; TP53; CDK19; HDAC6; HIST1H2AL; WWOX
Function histone methyltransferase binding
Related Protein CBX3; PRDM4; CBX1; NOP56
Function protein binding
Related Protein DOT1L; CEP76; ZKSCAN5; KCNQ4; IL11; MSLN; COPS3; UCP2; KCNJ10; FAP
Function protein homodimerization activity
Related Protein BARD1; TIMELESS; HELT; RENBP; TGFB2; ENO2; KCNH2; FBXO4; PEX11A; SP1

Interacting Protein

CBX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CBX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CBX1.
HIST1H3D; Mad2l2; CHAF1A; CBX5; POGZ; CHAMP1