CCNG1
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Official Full Name
cyclin G1
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Overview
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene. -
Synonyms
CCNG1; cyclin G1; CCNG; cyclin-G1; CCNG 1; CCNG1_HUMAN; CYCG1; Cyclin G; Cyclin-G; OTTHUMP00000160918; OTTHUMP00000223690; OTTHUMP00000223692; OTTHUMP00000223697;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Sf9 Insect Cell
- Wheat Germ
- DDK
- GST
- GST|His
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CCNG1-1331H | Recombinant Human Cyclin G1, His-tagged | E.coli | His |
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| Human | CCNG1-824H | Recombinant Human CCNG1 Protein, DDK-tagged | Sf9 Insect Cell | DDK |
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| Human | CCNG1-825H | Recombinant Human CCNG1 Protein, GST-His-tagged | E.coli | GST/His |
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| Human | CCNG1-28189TH | Recombinant Human CCNG1 | Wheat Germ | N/A | 295 amino acids |
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| Human | CCNG1-0669H | Recombinant Human CCNG1 Protein, GST-Tagged | Wheat Germ | GST |
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| Human | CCNG1-26094TH | Recombinant Human CCNG1, His-tagged | E.coli | His | 295 amino acids |
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| Human | CCNG1-7707HCL | Recombinant Human CCNG1 293 Cell Lysate | HEK293 | N/A |
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| Human | CCNG1-3613H | Recombinant Human CCNG1 protein, GST-tagged | E.coli | GST | 1-46 aa | |
| Human | CCNG1-53HF | Recombinant Full Length Human CCNG1 Protein | In Vitro Cell Free System | 295 amino acids |
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| Human | CCNG1-2974HF | Recombinant Full Length Human CCNG1 Protein, GST-tagged | In Vitro Cell Free System | GST | 295 amino acids |
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| Mouse | CCNG1-2995M | Recombinant Mouse CCNG1 Protein | Mammalian Cell | His |
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| Mouse | CCNG1-1408M | Recombinant Mouse CCNG1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | CCNG1-1408M-B | Recombinant Mouse CCNG1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | CCNG1-1224R | Recombinant Rat CCNG1 Protein | Mammalian Cell | His |
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| Rat | CCNG1-882R-B | Recombinant Rat CCNG1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | CCNG1-882R | Recombinant Rat CCNG1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Zebrafish | CCNG1-9922Z | Recombinant Zebrafish CCNG1 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
CCNG1 involved in several pathways and played different roles in them. We selected most pathways CCNG1 participated on our site, such as p signaling pathway, MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCNG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| p signaling pathway | IGFBP3;CDK1;MDM2;ATM;CASP3B;TSC2;SIAH2L;RRM2B;RCHY1 |
| MicroRNAs in cancer | CCND2;FZD3;PTGS2;NOTCH1;Casp3;PLCG1;ZFPM2;SHC4;TRP63 |
CCNG1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCNG1 itself. We selected most functions CCNG1 had, and list some proteins which have the same functions with CCNG1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | FKBP1A;CTDSP1;APLP1;FRMPD4;STAU2;CUL4B;MTAP1A;DLGAP4;NPY1R |
CCNG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCNG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCNG1.
TNIP1; KRTAP10-7; KRT40; HMBOX1; SPERT; PNMA1
- Q&As
- Reviews
Q&As (7)
Ask a questionTargeting CCNG1 in cancer therapy could help control tumor growth by affecting cell cycle dynamics.
Dysregulated CCNG1 expression is linked with the advancement of various cancers due to its role in cell cycle control.
CCNG1, as a cyclin, regulates the cell cycle, particularly the transition between phases.
It contributes to cellular senescence by influencing cell cycle arrest mechanisms.
Mutations in CCNG1 can lead to aberrant cell cycle progression, potentially resulting in cancer.
CCNG1 works in tandem with other cell cycle proteins and signaling pathways to regulate cell division.
CCNG1 plays a role in DNA damage response, helping to maintain genomic stability.
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