ccr8
Share
  • Official Full Name
  • chemokine (C-C motif) receptor 8
  • Background
  • CCR8 (C-C chemokine receptor 8, CKR-L1, cy6) is a member of the beta-chemokine receptor family that is preferentially expressed in the thymus. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites
  • Synonyms
  • CCR8; chemokine (C-C motif) receptor 8; CMKBR8, CMKBRL2; C-C chemokine receptor type 8; CDw198; CKR L1; CY6; GPR CY6; TER1; CC chemokine receptor 8; chemokine receptor-like 1; chemokine (C-C) receptor 8; CC chemokine receptor CHEMR1; CC-chemokine receptor
Cat.#:CCR8-0697HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CCR8 Protein
+Inquiry
Cat.#:CCR8-0698HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CCR8 Protein, GST-Tagged
+Inquiry
Cat.#:CCR8-3018MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CCR8 Protein
+Inquiry
Cat.#:CCR8-380CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CCR8 Protein, His-tagged
+Inquiry
Cat.#:CCR8-2675CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CCR8
+Inquiry
Cat.#:Kit-0878Tag:
Source (Host):Species:
Product nameADK Phosphorylation Assay Kit
+Inquiry
Cat.#:Kit-1162Tag:
Source (Host):Species:
Product nameCCR8 CHO-K1 β-Arrestin GPCR Assay Kit
+Inquiry

Involved Pathway

CCR8 involved in several pathways and played different roles in them. We selected most pathways CCR8 participated on our site, such as Chemokine receptors bind chemokines, Chemokine signaling pathway, Class A/1 (Rhodopsin-like receptors), which may be useful for your reference. Also, other proteins which involved in the same pathway with CCR8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Chemokine receptors bind chemokines
CCR1; CXCL13; CCL19A.2; CCL35.1; CCL27; CXCR7B; CCR3; CX3CR1; CCRL2; AMCF-II
Chemokine signaling pathway
CXCL3; PRKACG; GNG7; MAPK3; SHC4; ELMO1; CXCR3; GNB1; CXCR5; XCL2
Class A/1 (Rhodopsin-like receptors)
SST1.1; AMCF-II; CHRM2; ADRA2C; OXGR1A.1; NMBA; GPR37L1; TAC1; GAL; RGS1
Cytokine-cytokine receptor interaction
PPBP; IFNG1-2; OSM; CRFB16; IL22RA1; CRFB2; IL1RAP; KIT; GM10591; CNTF
G alpha (i) signalling events
LPAR5A; PENKA; GPR18; S1PR3; OXGR1A.1; PNOC; NMUR1; NMS; PTGDR2; CNR1
GPCR downstream signaling
ANXA1A; ANXA1; ARHGEF18; NPS; CCL35.2; CCK; APLNR; RGS6; OXGR1; RGS1
GPCR ligand binding
OXGR1A.1; FPR-RS6; CALCA; GPR55; ADORA1; TAS2R13; OXER1; CRH; KEL; CCRL2
GPCRs, Class A Rhodopsin-like
GPR20; FPR-RS3; GPR85; GPR4; LTB4R; CCR3; HRH3; SSTR3; ADORA3; PTGDR2

Protein Function

CCR8 has several biochemical functions, for example, C-C chemokine receptor activity, chemokine receptor activity, coreceptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCR8 itself. We selected most functions CCR8 had, and list some proteins which have the same functions with CCR8. You can find most of the proteins on our site.
Function
Related Protein
Function C-C chemokine receptor activity
Related Protein CCR1; CCR9; CCR1L1; CCR3; CCR8; CCBP2; CCR6; GPR75; CCR7; CCR6A
Function chemokine receptor activity
Related Protein CX3CR1; CXCR3; RGRB; CXCR7B; CCR5; CCRL2; XCR1; CCR9; CCR1L1; ACKR3B
Function coreceptor activity
Related Protein RGMA; HFE2; RAMP3; LY96; CD80; CXCR6; RAMP1; CCR8; CD4; PVRL1

CCR8 Related Articles

Santos-Costa, Q; Lopes, MM; et al. HIV-2 interaction with cell coreceptors: amino acids within the V1/V2 region of viral envelope are determinant for CCR8, CCR5 and CXCR4 usage. RETROVIROLOGY 11:-(2014).
Zhou, JH; Kang, N; et al. Anti-gamma delta TCR antibody-expanded gamma delta T cells: a better choice for the adoptive immunotherapy of lymphoid malignancies. CELLULAR & MOLECULAR IMMUNOLOGY 9:34-44(2012).

CCR8 Related Gene Family

Chemokines Cytokines