cdc7
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  • Official Full Name
  • cell division cycle 7 homolog
  • Background
  • The initiation of DNA replication in mammalian cells is a highly coordinated process that ensures duplication of the genome only once per cell division cycle. Origins of replication are dispersed throughout the genome, and their activities are regulated v
  • Synonyms
  • CDC7; cell division cycle 7 homolog (S. cerevisiae); CDC7 (cell division cycle 7, S. cerevisiae, homolog) like 1 , CDC7 cell division cycle 7 (S. cerevisiae) , CDC7L1, cell division cycle 7 (S. cerevisiae); cell division cycle 7-related protein kinase
Cat.#:CDC7-0957HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CDC7 Protein, GST-Tagged
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Cat.#:CDC7-0958HTag:GST
Source (Host):Insect CellSpecies:Human
Product nameRecombinant Human CDC7 Protein, GST-Tagged
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Cat.#:CDC7-021HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDC7 Protein, His-tagged
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Cat.#:CDC7-11019HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDC7, His-tagged
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Cat.#:CDC7-22HTag:GST
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human CDC7/DBF4 Protein, GST-tagged
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Cat.#:CDC7-770RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CDC7 Protein, His-tagged
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Cat.#:CDC7-1793ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CDC7
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Cat.#:CDC7-997HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Cell Division Cycle 7 Homolog (S. cerevisiae), GST-tagged
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Cat.#:CDC7-7646HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CDC7 293 Cell Lysate
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Involved Pathway

CDC7 involved in several pathways and played different roles in them. We selected most pathways CDC7 participated on our site, such as Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC7 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell cycle
MND1; RBX1; E2F4; YWHAE2; CKS1B; H3F3B.1; BUB1B; TUBB4A; FGFR1OP; YWHAE1

Protein Function

CDC7 has several biochemical functions, for example, ATP binding, kinase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC7 itself. We selected most functions CDC7 had, and list some proteins which have the same functions with CDC7. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PTK2B; PIK3C2G; PRKAG3; RIPK4; AGK; ADCY6; CHD2; UBE2A; UCKL1A; P2RX4B
Function kinase activity
Related Protein CKBB; CAMK2D2; SPS2; PKZ; DNAJC3B; ACVR1L; PRKG1A; STK35L; CAMK1GB; KALRN
Function metal ion binding
Related Protein POLR3A; CYBA; KLF15; ATF7B; TSHZ1; ZFP354A; BCMO1; PGCP; KIT; KCND1
Function protein binding
Related Protein PPP1R9A; RPS7; TRAF1; PPP3R2; CSF3R; SLAMF7; TNFSF13B; RABL2; DNA2; TCAP
Function protein kinase activity
Related Protein MAK; PTK7A; RPS6KA3; CHEK1; PDPK1A; NPRL2; PRKACAB; BMPR2B; INSRB; STK38A
Function protein serine/threonine kinase activity
Related Protein STRC; MAP4K6; MAP4K4; GAK; SRPK1B; TP53RK; SBK3; CLK3; CDC7; MARK1

Interacting Protein

CDC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC7.
MCMBP; ORC5; CDK4; MCM3; CDKN1A; CDKN2A; MCM2; MCM10; ORC6; CHAF1A; DBF4; GPT; CDK9; GRHPR

CDC7 Related Articles

Hou, Y; Wang, HQ; et al. Effects of CDC7 gene silencing and Rituximab on apoptosis in diffuse large B cell lymphoma cells. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 138:2027-2034(2012).
Charych, DH; Coyne, M; et al. Inhibition of Cdc7/Dbf4 kinase activity affects specific phosphorylation sites on MCM2 in cancer cells. JOURNAL OF CELLULAR BIOCHEMISTRY 104:1075-1086(2008).