CDC7 Protein, cell division cycle 7 homolog

CDC7

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CDC7

Official Full Name cell division cycle 7 homolog
Background The initiation of DNA replication in mammalian cells is a highly coordinated process that ensures duplication of the genome only once per cell division cycle. Origins of replication are dispersed throughout the genome, and their activities are regulated v
Synonyms CDC7; cell division cycle 7 homolog (S. cerevisiae); CDC7 (cell division cycle 7, S. cerevisiae, homolog) like 1 , CDC7 cell division cycle 7 (S. cerevisiae) , CDC7L1, cell division cycle 7 (S. cerevisiae); cell division cycle 7-related protein kinase
    • Species :
    • Human
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDC7-021H Recombinant Human CDC7 Protein, His-tagged E.coli His
    Human CDC7-0957H Recombinant Human CDC7 Protein, GST-Tagged Wheat Germ GST
    Human CDC7-0958H Recombinant Human CDC7 Protein, GST-Tagged Insect Cell GST
    Human CDC7-11019H Recombinant Human CDC7, His-tagged E.coli His
    Human CDC7-22H Recombinant Human CDC7/DBF4 Protein, GST-tagged Insect Cell GST
    Human CDC7-7646HCL Recombinant Human CDC7 293 Cell Lysate HEK293 N/A
    Human CDC7-997H Recombinant Human Cell Division Cycle 7 Homolog (S. cerevisiae), GST-tagged Sf9 Insect Cell GST
    Rhesus Macaque CDC7-770R Recombinant Rhesus monkey CDC7 Protein, His-tagged Mammalian Cell His
    Zebrafish CDC7-1793Z Recombinant Zebrafish CDC7 Mammalian Cell His

    CDC7 involved in several pathways and played different roles in them. We selected most pathways CDC7 participated on our site, such as Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell cycle PCM1; CEP57; NEDD1; CDH1-A; MYC; MSH5; MCM2; SMC1B; CENPE; CDC16

    CDC7 has several biochemical functions, for example, ATP binding, kinase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC7 itself. We selected most functions CDC7 had, and list some proteins which have the same functions with CDC7. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding CARNS1; IARS2; PAPOLB; NEK2; NAV2; EPHA4; NRBP1; HK1; BTK; ACSL4
    kinase activity BCKDK; AKT3A; DCLK3; ACVR1L; BMPR1AA; CLK4B; MAPKAPK2A; PRKD3; CKBB; CAMK2D1
    metal ion binding RUNX1T1; VDRA; IKZF1; DOM3Z; ZNF502; CYP46A1.1; CYP2K22; NR6A1B; PRKD1; ZNF213
    protein binding GLI3; MORN3; ANKRD32; DCTN2; CDYL2; TRMT12; EIF4B; ITGB3; AP1M2; TEX10
    protein kinase activity RIPK3; LIMK1; CDK8; STK38A; FYNA; PAK1; CSNK1G2A; NPR1A; CASKA; SYK
    protein serine/threonine kinase activity PDIK1L; STK38L; CHEK1; PRKCQ; PHKG2; BRAF; MTOR; SYK; EIF2AK4; CAMK2D2

    CDC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC7.

    MCMBP; ORC5; CDK4; MCM3; CDKN1A; CDKN2A; MCM2; MCM10; ORC6; CHAF1A; DBF4; GPT; CDK9; GRHPR

    Hou, Y; Wang, HQ; et al. Effects of CDC7 gene silencing and Rituximab on apoptosis in diffuse large B cell lymphoma cells. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 138:2027-2034(2012).
    Charych, DH; Coyne, M; et al. Inhibition of Cdc7/Dbf4 kinase activity affects specific phosphorylation sites on MCM2 in cancer cells. JOURNAL OF CELLULAR BIOCHEMISTRY 104:1075-1086(2008).

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