cdh6
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  • Official Full Name
  • cadherin 6, type 2, K-cadherin (fetal kidney)
  • Background
  • This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.
  • Synonyms
  • CDH6; cadherin 6, type 2, K-cadherin (fetal kidney); cadherin-6; K Cadherin; CAD6; KCAD; FLJ14176; DKFZp564N1116
Cat.#:CDH6-1102CTag:His
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus CDH6 Protein (Met1-Gly614), His-tagged
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Cat.#:CDH6-0992HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CDH6 Protein, GST-Tagged
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Cat.#:CDH6-070HTag:HIS
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human CDH6 Protein, HIS-tagged
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Cat.#:CDH6-071HTag:Fc
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human CDH6 Protein, Fc-tagged
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Cat.#:CDH6-110HTag:T7/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDH6 protein, T7/His-tagged
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Cat.#:CDH6-668HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CDH6, His tagged
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Cat.#:Cdh6-593MTag:His
Source (Host):NSO CellsSpecies:Mouse
Product nameRecombinant Mouse Cdh6 Protein, His-tagged
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Cat.#:Cdh6-7411MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Cdh6, His tagged
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Cat.#:CDH6-1098RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CDH6 Protein, His-tagged
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Cat.#:CDH6-1294RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CDH6 Protein
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Cat.#:CDH6-1154CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CDH6
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Cat.#:CDH6-2187ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CDH6
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Cat.#:CDH6-2727HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CDH6 cell lysate
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Cat.#:CDH6-1478MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CDH6 cell lysate
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Involved Pathway

CDH6 involved in several pathways and played different roles in them. We selected most pathways CDH6 participated on our site, such as Adherens junctions interactions, Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDH6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adherens junctions interactions
CADM2; PVRL2L; CDH12A; CDH18A; CDH9; PVRL1A; CADM2B; CTNNB1; CTNNA1; CDH10
Cell junction organization
CDH13; CLDN7; CLDN16; CLDN3; CTNND1; CDH8; PLEC; CLDN20; CADM2B; CADM2
Cell-Cell communication
INADL; CLDN3; CDH18A; CLDN7; JUP; SIRPB1; CLDN4; DSCAMA; CDH2; CADM2
Cell-cell junction organization
CADM2A; CDH12; CDH7; PVRL2L; CLDN4; CLDN7; CLDN23; ANG; CDH10; CDH12A
Neural Crest Differentiation
LHX1; SOX10; TCF4; ASCL1; PMP22; OLIG3; CDH6; ZIC1; CDH7; PHOX2B

Protein Function

CDH6 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH6 itself. We selected most functions CDH6 had, and list some proteins which have the same functions with CDH6. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein S100A8; THBS3; CAPN2A; CELSR2; REPS1; MMP8; ANXA2B; PLCZ1; PCDHB13; EHD1B

CDH6 Related Articles

Butler, MG; Rafi, SK; et al. Whole Exome Sequencing in Females with Autism Implicates Novel and Candidate Genes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 16:1312-1335(2015).
Clay, MR; Halloran, MC; et al. Cadherin 6 promotes neural crest cell detachment via F-actin regulation and influences active Rho distribution during epithelial-to-mesenchymal transition. DEVELOPMENT 141:2506-2515(2014).