ces5a
Share
  • Official Full Name
  • carboxylesterase 5A
  • Background
  • This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene, also called CES5, is predominantly expressed in peripheral tissues, including brain, kidney, lung and testis. It encodes a secreted enzyme. Because of high levels in the urine of male domestic cats, this enzyme is also called cauxin (carboxylesterase-like urinary excreted protein). The enzyme functions in regulating the production of a pheromone precursor and may contribute to lipid and cholesterol transfer processes within male reproductive fluids. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • CES5A; carboxylesterase 5A; carboxylesterase 7 , CES7; CAUXIN; CES4C1; CES5; FLJ31547; Carboxylesterase 5; Carboxylesterase 7; Carboxylesterase like urinary excreted protein; Carboxylesterase like urinary excreted protein homolog; CES 7; EC 3.1.1.1; carboxylesterase-like urinary excreted protein homolog; CES7
Cat.#:CES5A-5238HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CES5A Protein, GST-tagged
+Inquiry
Cat.#:CES5A-1351RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CES5A Protein
+Inquiry
Cat.#:CES5A-823RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CES5A Protein, His-tagged
+Inquiry
Cat.#:CES5A-7563HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CES7 293 Cell Lysate
+Inquiry
Cat.#:CES5A-2231MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CES5A cell lysate
+Inquiry

Involved Pathway

CES5A involved in several pathways and played different roles in them. We selected most pathways CES5A participated on our site, such as E2F transcription factor network, Phase I, non P450, retinol biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CES5A were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
E2F transcription factor network
E2F6; CES3; E2F4; CES1; TRIM28; CBX5; CEBPA; HIC1; MYBL2; RBBP8
Phase I, non P450
CES5A
retinol biosynthesis
RBP5; DHRS9; CES5A; DHRS4

Protein Function

CES5A has several biochemical functions, for example, sterol esterase activity, triglyceride lipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CES5A itself. We selected most functions CES5A had, and list some proteins which have the same functions with CES5A. You can find most of the proteins on our site.
Function
Related Protein
Function sterol esterase activity
Related Protein Cel; LIPA; CES1; CEL.1; CES3; CES5A; CES1D
Function triglyceride lipase activity
Related Protein LIPCA; AADAC; PNLIPRP3; CEL.1; CES1; PNLIPRP1; PNLIP; PNPLA3; PNPLA4; PNPLA2