CHD7 Protein, chromodomain helicase DNA binding protein 7


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Official Full Name chromodomain helicase DNA binding protein 7
Background This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. [provided by RefSeq, Jul 2008]
Synonyms CHD7; chromodomain helicase DNA binding protein 7; CRG; HH5; IS3; KAL5; chromodomain-helicase-DNA-binding protein 7; CHARGE association; ATP-dependent helicase CHD7; chromodomain helicase DNA binding protein 7 isoform CRA_e;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CHD7-1216H Recombinant Human CHD7 Protein E.coli N/A
    Human CHD7-4914H Recombinant Human Chromodomain Helicase DNA Binding Protein 7, His-tagged E.coli His
    Mouse CHD7-3382M Recombinant Mouse CHD7 Protein Mammalian Cell His
    Chicken CHD7-3513C Recombinant Chicken CHD7 Mammalian Cell His

    CHD7 involved in several pathways and played different roles in them. We selected most pathways CHD7 participated on our site, such as Noncanonical Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHD7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Noncanonical Wnt signaling pathway CHD7; CTHRC1; ROR2

    CHD7 has several biochemical functions, for example, ATP binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHD7 itself. We selected most functions CHD7 had, and list some proteins which have the same functions with CHD7. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding CCC2; FER; UBE2QL1; ACSL5; RPS6KB2; ROR2; STK26; ABCC8; PRKCA; KIF2A
    RNA polymerase II core promoter proximal region sequence-specific DNA binding DPF2; NR1H2; MYF6; ISL1; MYPOP; CTCFL; NFATC2; BCL11A; ZNF502; HOXA10
    chromatin binding TFAM; ZFP932; SIN3A; MEIS3; CDC45; GATA5; SMARCD3; PRIMPOL; MEN1; MCMBP
    helicase activity MCM9; HELLS; SETX; SHPRH; SMARCA4; DDX51; RAD54L; EIF4A1A; BLM; EIF4A2
    protein binding KCNJ9; CBS; DEAF1; KRT20; BMX; DNER; GSE1; ACTB; GTPBP2; C6orf108

    CHD7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHD7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHD7.

    CHD8; CHD8; gli2_human_gene; jag1_human_gene; gli3_human_gene; mycn_human_gene; necd_human_gene; CBX4; NES; SNW1

    Yamada, M; Sato, N; et al. Association of the Chromodomain Helicase DNA-Binding Protein 4 (CHD4) Missense Variation p.D140E with Cancer: Potential Interaction with Smoking. GENES CHROMOSOMES & CANCER 54:122-128(2015).
    Lee, SJ; Chae, JH; et al. Non-Homologous End Joining Repair Mechanism-Mediated Deletion of CHD7 Gene in a Patient with Typical CHARGE Syndrome. ANNALS OF LABORATORY MEDICINE 35:141-145(2015).

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