Recombinant Human Chromodomain Helicase DNA Binding Protein 7, His-tagged

Cat.No. : CHD7-4914H
Product Overview : Recombinant full length human CHD7 containing N-terminal His tag was expressed by E. coli.
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Cat. No. : CHD7-4914H
Description : CHD7 is a N-terminal His-tagged recombinant protein and a member of the Sso7d family of small, abundant, non-specific DNA-binding proteins from the hyperthermophilic Archea Sulfolobus. The 7-kDa protein from Sulfolobus spp. consists of a five stranded, incomplete β-barrel capped at the opening by a C-terminal α-helix; they bind to the minor groove of a DNA duplex via the triple-stranded β-sheet.
Molecular Weight : 9.44 kDa
Source : E. coli
Species : Human
Form : Sterile filtered and lyophilized with no additives.
Appearance : Lyophilized protein
Sequence : MGSSHHHHHHSSGLVPRGSHMATVK FKYKGEEKEVDISKIKKVWRVGKMI SFTYDEGGGKTGRGAVSEKDAPKEL LQMLEKQKK
Endotoxin Level : <0.1 ng/μg
Reconstitution : Centrifuge the vial prior to opening. Reconstitute in ddH2O to a concentration of 1.0 mg/ml. Aliquot and store at -20°C for future use. Repeated freeze/thaw cycles should be avoided.
Purity : >99% by SDS-PAGE
Storage : The lyophilized CHD7 is best-stored desiccated below 0°C. Reconstituted protein should be stored in working aliquots at -20°C.
Pathways : Noncanonical Wnt signaling pathway
SDS-PAGE:
Gene Name : CHD7 chromodomain helicase DNA binding protein 7 [ Homo sapiens ]
Official Symbol : CHD7
Synonyms : CHD7; chromodomain helicase DNA binding protein 7; IS3; KAL5; FLJ20357; FLJ20361; KIAA1416; chromodomain-helicase-DNA-binding protein 7; OTTHUMP00000229376; ATP-dependent helicase CHD7; chromodomain helicase DNA binding protein 7 isoform CRA_e; EC 3.6.4.12
Gene ID : 55636
mRNA Refseq : NM_017780
Protein Refseq : NP_060250
MIM : 608892
UniProt ID : Q9P2D1
Chromosome Location : 8q12.2
Function : ATP binding; DNA binding; chromatin binding; helicase activity; hydrolase activity, acting on acid anhydrides; nucleotide binding

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