|Official Full Name||cholinergic receptor, nicotinic, beta 1 (muscle)|
|Background||The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.|
|Synonyms||CHRNB1; cholinergic receptor, nicotinic, beta 1 (muscle); acetylcholine receptor subunit beta; Acetylcholine receptor protein beta chain precursor; ACHB_HUMAN; ACHRB; Cholinergic receptor nicotinic beta polypeptide 1 (muscle); Chrnb 1; CHRNB; CMS1D; CMS2A; Nicotinic acetylcholine receptor beta subunit precursor; SCCMS; cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CHRNB1 involved in several pathways and played different roles in them. We selected most pathways CHRNB1 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHRNB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Neuroactive ligand-receptor interaction||GRM2A; THRA; CSH2; KISS1R; KISS1RB; PTGER2B; GLRBB; TAAR10D; MLNR; ADORA2AB|
CHRNB1 has several biochemical functions, for example, contributes_to acetylcholine binding, acetylcholine binding, contributes_to acetylcholine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHRNB1 itself. We selected most functions CHRNB1 had, and list some proteins which have the same functions with CHRNB1. You can find most of the proteins on our site.
|contributes_to acetylcholine binding||CHRNB3B; CHRNB1; CHRNA2; CHRNB4; CHRNA1; CHRNA4; CHRNA6; CHRNA5; CHRNA10A; CHRNA2A|
|acetylcholine binding||CHRNB2; CHRNB3; ACHE; CHRNB1; CHRNA7; CHRM3; CHRNA3; CHRFAM7A; CHRNA4|
|contributes_to acetylcholine receptor activity||CHRND; CHRNB1L; CHRNA2A; CHRNA10A; ZACN; CHRNB3A; CHRNB1; CHRNB3B; CHRNA9; CHRNA4B|
|contributes_to acetylcholine-activated cation-selective channel activity||CHRNB3B; CHRNB1L; CHRNA10A; ZACN; CHRNA4B; CHRNB3A; CHRNA9; CHRNA1; CHRNA10; CHRFAM7A|
|channel activity||PANX2; PANX1B; P2RX6; STEAP1; TRPA1; BAXB; BCL2; BAXA; PANX1A; CHRNB1|
|ligand-gated ion channel activity||ANXA6; CHRNB4; CHRNA4; P2RX2; CHRNA5; CLCA2; Chrng; ZACN; CHRNA3; CHRNB1|
CHRNB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHRNB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHRNB1.