Recombinant Human CHRNB1 Protein, GST-Tagged

• Cat.No.: CHRNB1-1285H
• Product Overview: Human CHRNB1 partial ORF (NP_000738, 24 a.a. - 128 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 37.29 kDa
• AA Sequence: SEAEGRLREKLFSGYDSSVRPAREV GDRVRVSVGLILAQLISLNEKDEEM STKVYLDLEWTDYRLSWDPAEHDGI DSLRITAESVWLPDVVLLNNNDGNF DVALD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) [ Homo sapiens ]
• Official Symbol: CHRNB1
• Synonyms: CHRNB1; cholinergic receptor, nicotinic, beta 1 (muscle); cholinergic receptor, nicotinic, beta polypeptide 1 (muscle), CHRNB; acetylcholine receptor subunit beta; acetylcholine receptor; nicotinic; beta 1 (muscle); acetylcholine receptor, nicotinic, beta 1 (muscle); cholinergic receptor, nicotinic, beta polypeptide 1 (muscle); ACHRB; CHRNB; CMS1D; CMS2A; SCCMS; FLJ57107
• Gene ID: 1140
• mRNA Refseq: NM_000747
• Protein Refseq: NP_000738
• MIM: 100710
• UniProt ID: P11230