CHST13

  • Official Full Name

    carbohydrate (chondroitin 4) sulfotransferase 13

  • Overview

    The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices.

  • Synonyms

    CHST13;carbohydrate (chondroitin 4) sulfotransferase 13;carbohydrate sulfotransferase 13;C4ST3;C4ST 3;C4ST-3;Chondroitin 4 O sulfotransferase 3;Chondroitin 4 sulfotransferase 3;Chondroitin 4-O-sulfotransferase 3;Chondroitin 4-sulfotransferase 3;CHST 13;CHSTD_HUMAN;MGC119278;MGC119279;MGC119281

Recombinant Proteins

  • Human
  • Rhesus macaque
  • E.coli
  • Wheat Germ
  • Mammalian Cells
  • In Vitro Cell Free System
  • HEK293
  • His
  • GST
  • Non
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CHST13-11226H Recombinant Human CHST13, His-tagged E.coli Human His 1-110a.a.
CHST13-1340H Recombinant Human CHST13 Protein, GST-tagged Wheat Germ Human GST
CHST13-868R Recombinant Rhesus monkey CHST13 Protein, His-tagged Mammalian Cells Rhesus macaque His
CHST13-354HCL Recombinant Human CHST13 cell lysate Human Non
CHST13-1830HF Recombinant Full Length Human CHST13 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 225 amino acids
CHST13-694R Recombinant Rhesus Macaque CHST13 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
CHST13-694R-B Recombinant Rhesus Macaque CHST13 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque

    Involved Pathway

    CHST13 involved in several pathways and played different roles in them. We selected most pathways CHST13 participated on our site, such as Activated TLR4 signalling,Cytosolic sensors of pathogen-associated DNA,DEx/H-box helicases activate type I IFN and inflammatory cytokines production, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Immune System NLRP4E,GBP6,ASB7,TAX1BP1,ASB2,NPEPPS,TAX1BP1B,IFIT8,TNFRSF13C,RAPGEF4
    DEx/H-box helicases activate type I IFN and inflammatory cytokines production APPB,ALCAMB,AGER,S100B,APPA,S100A12,SAA1,DHX9
    Cytosolic sensors of pathogen-associated DNA DDX41,DHX9,NLRP4B,CRCP,NLRP4,POLR3G,LRRFIP1,POLR3H,AGER,TICAM1
    Innate Immune System IRAK3,NOD1,PANX1B,CNPY3,LY86,PELI2,DEFB1,CASP4,WIPF2,DEFB106A
    Gene Expression HNRNPA0B,ZNF157,EXOSC8,NRBF2,ZNF205,LAGE3,ZNF707,EEF1G,TH1L,ZNF10
    MyD88 dependent cascade initiated on endosome S100A12,S100B,DHX9,ALCAMB
    MyD88 cascade initiated on plasma membrane DUSP3B,TLR10,PELI2,AGER,DHX9,PELI1,S100A12,TNIP2,PELI3,S100B
    Activated TLR4 signalling JUN,DUSP4,MAPK14,IRAK3,NOD1,DUSP7,APPA,APPB,SAA1,PELI1

    Protein Function

    CHST13 has several biochemical functions, for example, ATP binding,ATP-dependent DNA helicase activity,ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST13 itself. We selected most functions CHST13 had, and list some proteins which have the same functions with CHST13. You can find most of the proteins on our site.

    Function Related Protein
    ATP-dependent DNA helicase activity WRN,G3BP1,XRCC5,CHD4,ERCC3,BLM,XRCC6,FBXO18,RUVBL2,DDX3X
    DNA binding ZNF221,AEBP1,NR0B2,ZBTB41,SP8,ZNF319,ZNF518A,ZNF212,DRAP1,ZNF511
    protein binding NDNL2,APOL1,EPHA2,DOK3,TBC1D10A,MAGEF1,SURF1,DNA2,HSPB2,BTK
    ATP binding RARS2,RIPK1L,ABCB6,RUNX2B,SETX,PIP5KL1,STK30,MAPK10,PIP5K2,VSIG8B
    RNA helicase activity CTU1,DDX6,DDX10,DHX16,PRIM2,DDX17,SKIV2L2,DDX5,UAP1L1,DHX15
    RNA polymerase II transcription factor binding TAL1,TRP53,DHX9,GATA2B,ATF4,WWP2,SFPI1,GATA5,SPOP,MTA2
    ATP-dependent RNA helicase activity ACTG2,DDX3Y,DQX1,DHX30,DDX4,DHX9,DHX33,DHX36,TDRD9,DDX39
    poly(A) RNA binding MRPS11,EIF4ENIF1,LRRC59,ANXA2,DEK,ATXN2L,RSRC2,CIRBP,HMGB1,RPS5

    Interacting Protein

    CHST13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHST13 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHST13.

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