chst3
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  • Official Full Name
  • carbohydrate (chondroitin 6) sulfotransferase 3
  • Background
  • This gene encodes an enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation. Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis.
  • Synonyms
  • CHST3; carbohydrate (chondroitin 6) sulfotransferase 3; carbohydrate sulfotransferase 3; C6ST; C6ST1; C6ST 1; C6ST-1; Chondroitin 6 O sulfotransferase 1; Chondroitin 6 sulfotransferase; Chondroitin 6-O-sulfotransferase 1; Chondroitin 6-sulfotransferase; CHST 3; CHST3_HUMAN; Galactose/N acetylglucosamine/N acetylglucosamine 6 O sulfotransferase 0; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0; GST 0; GST-0; GST0; OTTHUMP00000019779; HSD
Cat.#:CHST3-1343HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CHST3 Protein, GST-tagged
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Cat.#:CHST3-11229HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CHST3, GST-tagged
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Cat.#:CHST3-352HTag:His
Source (Host):CHO cellsSpecies:Human
Product nameRecombinant Human CHST3, His-tagged
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Cat.#:Chst3-4046MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Chst3, His tagged
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Cat.#:Chst3-705MTag:His
Source (Host):CHO CellsSpecies:Mouse
Product nameRecombinant Mouse Chst3 Protein, His-tagged
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Cat.#:CHST3-1407RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CHST3 Protein
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Cat.#:CHST3-6678CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CHST3
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Cat.#:CHST3-2072MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CHST3 cell lysate
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Involved Pathway

CHST3 involved in several pathways and played different roles in them. We selected most pathways CHST3 participated on our site, such as Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
CHPF2; DSE; B3GAT3; CHST12; CSGALNACT2; CSGALNACT1; CHST11; B4GALT7; CHST14; CHST3A

Protein Function

CHST3 has several biochemical functions, for example, N-acetylglucosamine 6-O-sulfotransferase activity, chondroitin 6-sulfotransferase activity, proteoglycan sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST3 itself. We selected most functions CHST3 had, and list some proteins which have the same functions with CHST3. You can find most of the proteins on our site.
Function
Related Protein
Function N-acetylglucosamine 6-O-sulfotransferase activity
Related Protein CHST2; HS6ST1B; CHST7; HS6ST3B; CHST3A; CHST3B; SULT2ST2; CHST2A; SULT2ST3; SULT1ST2
Function chondroitin 6-sulfotransferase activity
Related Protein CHST3; CHST7; CHST3A
Function proteoglycan sulfotransferase activity
Related Protein Chst5; SULT1ST7; SULT1ST8; HS6ST1A; CHST2; HS3ST3B1B; CHST3B; SULT6B1; SULT3ST2; SULT3ST3
Function sulfotransferase activity
Related Protein SULT2ST3; SULT1ST5; SULT1A2; WSCD1; HS3ST3A1; SULT1C4; HS3ST3L; GAL3ST1; SULT5A1; CHST3