CLDN8
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Official Full Name
Claudin 8
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Overview
This intronless gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a paracellular cation barrier. -
Synonyms
Cldn8; claudin 8; claudin-8; AI648025;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Rhesus Macaque
- Zebrafish
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CLDN8-1448H | Recombinant Human CLDN8 Protein, GST-tagged | Wheat Germ | GST |
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| Human | CLDN8-7458HCL | Recombinant Human CLDN8 293 Cell Lysate | HEK293 | N/A |
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| Human | CLDN8-2063HF | Recombinant Full Length Human CLDN8 Protein, GST-tagged | In Vitro Cell Free System | GST | 225 amino acids |
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| Homo sapiens (Human) | RFL20665HF | Recombinant Full Length Human Claudin-8(Cldn8) Protein, His-Tagged | E.coli expression system | His | Full Length (1-225) |
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| Rhesus Macaque | CLDN8-898R | Recombinant Rhesus monkey CLDN8 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | CLDN8-723R-B | Recombinant Rhesus Macaque CLDN8 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rhesus Macaque | CLDN8-723R | Recombinant Rhesus Macaque CLDN8 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Zebrafish | CLDN8-1075Z | Recombinant Zebrafish CLDN8 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- CLDN8 Related Articles
- CLDN8 Related Research Area
CLDN8 involved in several pathways and played different roles in them. We selected most pathways CLDN8 participated on our site, such as Cell adhesion molecules (CAMs), Tight junction, Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLDN8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell adhesion molecules (CAMs) | NLGN3;CDH4;HLA-DQA1;NEO1;CLDN7A;CD8B1;HLA-DRB1;BMA1;CLDN6 |
| Tight junction | PTEN;MYL10;TJP2;CLDNF;JAM3;MYH1C;EPB41L1;PPP2R2C;MPDZ |
| Leukocyte transendothelial migration | NOX1;CLDN20;GNAI3;PRKCB;ITGA4;NCF1;PIK3R1;PRKCA;TXK |
| Hepatitis C | IFNAR2;CLDN17;NFKBIA;IFNA4;NFKB1;PPP2R2B;CLDN11;CLDN1;IFNA14 |
CLDN8 has several biochemical functions, for example, identical protein binding, protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLDN8 itself. We selected most functions CLDN8 had, and list some proteins which have the same functions with CLDN8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | LDHA;CLDNG;CLDN2;CEACAM5;AGXT2L1;RGMB;ATXN10;TGFB3;NME1 |
| protein binding | RAB21;CBLB;SASS6;RBP5;KLHL3;RPL5;PHF16;ZFP57;USP54 |
| structural molecule activity | KRT35;CLDN15A;CLDNJ;MTAP7D2;CYLC1;KRT34;KRT73;COPB1;KRT33A |
CLDN8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLDN8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLDN8.
SYNE4; CCDC155
- Q&As
- Reviews
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