|Official Full Name||ceroid-lipofuscinosis, neuronal 3|
|Background||This gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]|
|Synonyms||CLN3; ceroid-lipofuscinosis, neuronal 3; BTS; JNCL; battenin; batten disease protein;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CLN3 involved in several pathways and played different roles in them. We selected most pathways CLN3 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Lysosome||SORT1B; ATP6V0CA; NPC1; CTNS; ATP6AP1; SORT1A; PSAPL1; SGSH; Ctsl; ATP6V0C|
CLN3 has several biochemical functions, for example, protein binding, unfolded protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLN3 itself. We selected most functions CLN3 had, and list some proteins which have the same functions with CLN3. You can find most of the proteins on our site.
|protein binding||SLC9A3R2; LARP4; LRPAP1; KNG1; C9orf100; ARPC2; ZNF302; IARS; RPL14; KIF20B|
|unfolded protein binding||CLN3; ST13; CCT7; HSPA1A; HSP90AA1.1; HSP104; CHAF1A; HSP90AA1; DNAJB13; CALR3B|
CLN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLN3.
ESYT2; XPO1; XPOT; ATG7; RPN2; CYC1; ABCD3; PHB; VDAC2; IRAK1; NPEPPS; GEMIN4; PRKDC; SLC25A11; GANAB; TRIP13; IMMT; HSD17B12; RIF1