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Official Full Name ceroid-lipofuscinosis, neuronal 6, late infantile, variant
Background This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.
Synonyms CLN6; ceroid-lipofuscinosis, neuronal 6, late infantile, variant; ceroid-lipofuscinosis neuronal protein 6; FLJ20561; HsT18960; nclf; CLN4A
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • C-Myc/DDK
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CLN6-112H Recombinant Human CLN6 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Mouse Cln6-2194M Recombinant Mouse Cln6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human CLN6-1507H Recombinant Human CLN6 Protein, GST-tagged Wheat Germ GST
    Human CLN6-7438HCL Recombinant Human CLN6 293 Cell Lysate HEK293 N/A
    Chicken CLN6-5007C Recombinant Chicken CLN6 Mammalian Cell His

    CLN6 involved in several pathways and played different roles in them. We selected most pathways CLN6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CLN6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    CLN6 has several biochemical functions, for example, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLN6 itself. We selected most functions CLN6 had, and list some proteins which have the same functions with CLN6. You can find most of the proteins on our site.

    Function Related Protein
    protein binding GTF2A1; LCAT; ASF1B; HDDC3; CLDN7; PTK2; KAT2A; PRKCZ; THAP7; SLPI
    protein homodimerization activity HEXB; HSF2; PDCD10; MAP3K5; BHLHA15; Il6ra; DST; IL12B; BAX; EIF2AK1

    CLN6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLN6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLN6.

    env; ILK; P

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