Recombinant Human CLN6 Protein, GST-tagged

• Cat.No.: CLN6-1507H
• Product Overview: Human CLN6 full-length ORF ( NP_060352.1, 1 a.a. - 311 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. [provided by RefSeq, Oct 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 62.3 kDa
• AA Sequence: MEATRRRQHLGATGGPGAQLGASFL QARHGSVSADEAARTAPFHLDLWFY FTLQNWVLDFGRPIAMLVFPLEWFP LNKPSVGDYFHMAYNVITPFLLLKL IERSPRTLPRSITYVSIIIFIMGAS IHLVGDSVNHRLLFSGYQHHLSVRE NPIIKNLKPETLIDSFELLYYYDEY LGHCMWYIPFFLILFMYFSGCFTAS KAESLIPGPALLLVAPSGLYYWYLV TEGQIFILFIFTFFAMLALVLHQKR KRLFLDSNGLFLFSSFALTLLLVAL WVAWLWNDPVLRKKYPGVIYVPEPW AFYTLHVSSRH
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant [ Homo sapiens ]
• Official Symbol: CLN6
• Synonyms: CLN6; ceroid-lipofuscinosis, neuronal 6, late infantile, variant; ceroid-lipofuscinosis neuronal protein 6; FLJ20561; HsT18960; nclf; CLN4A
• Gene ID: 54982
• mRNA Refseq: NM_017882
• Protein Refseq: NP_060352
• MIM: 606725
• UniProt ID: Q9NWW5